Signatera Basics
Draw Management & Logistics
Ordering in Epic
Financial Assistance
Tests & Turnaround Time
100

This is what MRD stands for.

What is Molecular Residual Disease?

100

These are the 3 ways a Signatera patient can have their blood collected.

What are the UCD Lab, Patient Service Centers, Mobile Phlebotomy?

100

This order must be placed in Epic alongside every initial Signatera order to notify the pathology department.


What is the Add-On Test/Consult Anatomical Pathology order?

100

A patient can enroll in Natera financial assistance by texting this word to this number.

What is CARE to 636363?

100

This is the turnaround time for the first Signatera test, and this is when the clock starts.

What is 3–4 weeks from when Natera receives the tissue sample?

200

This is what it means when Signatera is described as 'tumor-informed.

What is that the test is personalized to each patient's specific tumor mutation profile using their own tissue?

200

This is where Signatera kits are stocked at UC Davis.

What is the UCD Lab?

200

When a provider selects 'Natera manages all draws' and a patient walks into the UCD lab, this is what the lab sees and what must happen next.

What is an external order — and a new clinic/lab managed order must be placed?

200

This is how a patient making $100,000 per year with $15,000 in medical expenses should report their income on the financial assistance application.

What is $85,000?

200

This is the turnaround time for all subsequent Signatera draws, and this is when the clock starts.

What is 7–10 days from when Natera receives the blood sample?

300

This is how far in advance Signatera cadence orders build out when placed in Epic

What is 1 year (12 months)?

300

When a Natera-managed patient decides to draw at the UCD lab instead, this must happen before they can be collected.

What is placing a new clinic/lab managed order in Epic?

300

When a patient is switched from clinic-managed to Natera-managed, the patient will have orders on file in both of these places.

What are the UCD lab and Natera's system?

300

These are the only two pieces of information needed to complete the financial assistance application.

Response: What are household size and income?

300

This is what sets Latitude apart from Signatera Exome and Genome.

What is that Latitude is tumor-naïve and requires no tissue?

400

This is the default Signatera platform ordered unless a provider specifically requests otherwise.

What is Signatera Exome?

400

This is how many days a blood specimen remains stable at room temperature

What is 7 days?

400

These are all the cadence intervals available when placing a Signatera order in Epic.

What are 4 weeks, 6 weeks, 8 weeks, 3 months, and 6 months?

400

A patient can apply for Natera financial assistance through any of these three methods.

What are texting CARE to 636363, the online preliminary approval tool, and a paper fillable application?

400

This is what type of test Altera is, and this is when it must be ordered.

What is a Targeted Therapy Test — ordered at the same time as the initial Signatera order?

500

CRC patients are typically designed on this test/assay

What is Signatera Exome?

500

Until the UCD lab draws the patient and releases a clinic collect order, this is what Natera is unable to do.

What is see or access the new orders?

500

These are the two local Natera reps staff should contact to switch a patient from clinic-managed to mobile phlebotomy.

Who are Michelle Lee and MJ Cheema?

500

Although proof of income is required, Natera does not ask patients to provide proof of this.

What are medical expenses?

500

Once received at Natera, samples can be stored for this long."

What is up to 90 days?