Brand/Generics
The brand name for Terbinafine
What is Lamisil?
Honey-colored crusts
What is Impetigo?
This echinocandin can casue severe skin reactions (SJS/TEN).
Caspofungin
A patient experiences limited, localized impetigo lesions. What is the most appropriate therapy?
Topical Mupirocin
The brand name for Fluconazole.
What is Diflucan?
What type of fungi is Histoplasma capsulatum?
Dimorphic Fungi
A painful, compressible mass that is red, warm, and tender (swollen lump)
What is Abscess?
This antifungal can cause visual disturbances.
Voriconazole
A patient was bitten by an insect and has developed an abscess on her arm. She was given Bactrim for empiric therapy. Cultures came back and MSSA was identified. What antibiotic regimen would you recommend to de-escalate to?
Cephalexin
The brand name for Isavuconazonium.
What is Cresemba?
Contraindication of Isavuconazonium
Use with strong CYP3A4 inhibitors or inducers
Cottony feeling in the mouth
What is Oral thrush?
The black box warning for Ketoconazole.
Hepatotoxicity
A patient presents with mild oral thrush. What is the preferred empiric regimen?
Clotrimazole, Miconazole
The brand name for Micafungin.
What is Mycamine?
All azoles can cause ___ impairment
liver
A group of infected furuncles
What is Carbuncles?
The black box warning for Amphotericin B Deoxycholate.
Cardiopulmonary toxicity
A patient presents to the ED with meningitis from cryptococcus neoformans. What is the preferred regimen?
Amphotericin B + Flucytosine
The brand name for Miconazole.
What is Oravig?
All azoles can cause ___________ (except isavuconazonium)
QT prolongation
Destruction of muscle fascia (connective tissue) and subcutaneous fat
What is Necrotizing faciitis?
The black box warning for Flucytosine.
Use in extreme caution in patients with renal dysfunction; monitor hematologic, renal and hepatic status
Patient develops a bloodstream infection caused by C. krusei. Patient was previously on Caspofungin but symptoms have not improved. The culture is not sensitive to Fluconazole. What is an alternative regimen?
High dose amphotericin B