Basics
True or false: SNPs are mutations accumulated over time
What is false?
What is Genome-Wide Association Studies and analyzes SNPs?
40% percent of people suffer from this disease caused by uncontrolled mitosis
What is cancer?
A SNP in POLD1 will...
What is increase risk of tumor initiation & cancer progression?
This city is the capital of Mongolia
What is Ulaanbaatar?
What ADRS/ADES stands for
What is adverse drug reaction/adverse drug event?
True or false: AI is useless in SNP research
What is false?
11% of people suffer from this disease caused by neurological inflammation
What is Alzheimer's?
A SNP in APOE will...
What is eventually lead to Alzheimer’s disease?
(alters cholesterol transport and accumulates proteins leading to neuron deaths)
What is Sir Nicholas de Mimsy-Porpington (Nearly Headless Nick)?
What eSNP stands for and what function it interferes with
What is Expression SNP and gene expression?
What the X and Y axis of a SNP Manhattan Plot show
What is the location of the SNP on the chromosome and the -log 10 of the P-value?
1.2% of people suffer from this disease that is caused by electrical discharges in the brain
What is epilepsy?
A SNP in HLA will...
What is negatively affect the immune system?
(prevents proper distinguishing between the body's own cells and foreign invaders)
Name four aggregate fruits
What are any of the following: raspberry, blackberry, strawberry, custard apple, dewberry, magnolia, loganberry, boysenberry, clematis, delphinium?
What "SNP" stands for
What is Single Nucleotide Polymorphism?
What is when a patient's disorder cannot be affected or treated by proper medication (resistant to the drug); epilepsy
This is the number of globally identified SNPs (found across human populations)
What is >600 million?
A SNP in MTHFR will...
What is affect metabolism?
(methylenetetrahydrofolate reductase, processes folate and regulates homocysteine levels)
This was the cutoff for USABO opens in 2011
What is 29?
The difference between non-synonymous and synonymous SNPs
What is that nsSNPs change the amino acid/disrupt protein structure, while sSNPs do not change the amino acid?
What DeepVariant AI can be used for
What is improving SNP detection accuracy from high-throughput sequencing data?
The percent and amount of the human genome made up by SNPs
What is 0.1 - 0.4%, 4 - 5 million SNPs?
A SNP in CFH will...
What is causes macular degeneration?
(impaired vision in old age)
What an sparklebuttologist studies
What are fireflies?