General
Knowledge
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Important?
Safety
First
Memory
Tips
NCLEX RN
Facts
100

What does SNRI stand for?

What is serotonin and norepinephrine reuptake inhibitors

100

What is used to treat chronic pain and diabetes-related neuropathy?

What is duloxetine?

100

What are some OTC medications that should NOT be taken with an SNRI?

What is St. John's Wort, NSAIDs, dextromethorphan

100

Duloxetine treats mood and pain. What is a way to remember this?

What is Duloxetine = DUAL? 

100

A patient taking venlafaxine has a BP of 168/96 mmHg. This is the priority finding that the nurse should recognize as an adverse effect of the medication.

What is hypertension?

200

How do SNRIs work?

What is blocking reabsorption of serotonin and norepinephrine?

200

What is used to treat panic disorder and social anxiety disorder?

What is venlafaxine?
200

Taking St. John's wort or another antidepressant in combination with an SNRI can cause what condition?

What is serotonin syndrome

200

What can SNRI stand for in terms of discontinuation?

What is Sudden Nasty Rebound If stopped?

200

A patient is on an SNRI and reports taking an MAOI as well. This is the major reason the nurse should question the combination.

What is increased risk for serotonin syndrome?

300

True or false: the patient can stop taking SNRIs once they start feeling better.

What is false?

300

It is important to notify providers of an SNRI prescription before surgery because these medications can affect...

What is blood pressure?

300

What do people under 25 have an increased risk for during the first few weeks of taking an SNRI?

What are suicidal thoughts/behaviors

300
Three A's of serotonin syndrome
What is altered mental status, autonomic hyperactivity, and abnormal neuromuscular activity?
300

A patient states "I've been taking duloxetine for a week and I still don't feel any better." This is the teaching that the nurse should provide.

What is "It may take several weeks to experience the full therapeutic effect"?

400

How long do SSRIs typically take to work?

What is 4 to 6 weeks?

400

By restoring the balance of serotonin and norepinephrine, SNRIs affect...

What is mood, energy level, appetite, sleep, and focus?

400

How should an antidepressant be discontinued?

What is tapering?

400

Three S's (side effects) of SNRIs

What is sexual disfunction, sleep changes, stomach (GI upset/nausea)?

400

A patient states, "My depression is better, so I'm going to stop taking my SNRI tomorrow." The nurse is concerned about this statement and should provide further education on...

What is SNRI discontinuation syndrome/withdrawal?

500

The most common possible side effects of SNRIs include...

What is upset stomach, dry mouth, dizziness, headache, and sweating

500

SNRIs affect mood through ___ and alertness/energy through ____.

What is serotonin and norepinephrine?

500

A patient comes in the ER experiencing increased anxiety, agitation, high fever, confusion, tremors, lack of coordination, and high heart rate. What do you suspect?

What is serotonin syndrome

500

What does Vexed and Depressed stand for?

What are types of SNRIs?

Vexed = Venlafaxine

Depressed = Duloxetine and Desvenlafaxine

500

A patient without depression tells the nurse that they have been taking duloxetine every day. This condition could explain why the medication was prescribed.

What is chronic neuropathic pain?