Brain Regions
Dysfunction in ASD
Rodent Model Studies
100

This region of the brain contributes to top-down regulation and social decision making by integrating input from other regions of the brain. 

a. the insular cortex

b. the medial prefrontal cortex

c. the hypothalamus

What is...b. the medial prefrontal cortex?

100

Which of the following is not a social deficit seen in ASD?

a. reduced social motivation

b. difficulty making eye contact

c. deceiving intent/motives

What is....c. deceiving intent/motives?

100

This is the most popular mouse line used to model ASD in research.

a. BTBR mice

b. CNTNAP2 KO mice

c. Shank3 KO mice

What is....c. Shank3 KO mice?

200

This tool of study in the brain records electrical activity in the brain, such as electrical currents and neuronal communication, using various methods. 

a. optogenetics

b. electrophysiology

c. electroshock therapy

What is....b. electrophysiology?

200

Imbalance between these two items results in social behavior deficits and characterizes EEGs of children with ASD.

a. excitation and inhibition

b. opsins and modified genes

c. c-Fos and EEGs

What is...a. excitation and inhibition? 

200

Shank3 gene mutations can only account for this percent of human ASD prevalence.

a. 1%

b. 5%

c. 15%


What is....a. 1%?

300

This mPFC circuit is responsible for social avoidance and preference.

a. mPFC-hypothalamus

b. mPFC-amygdala

c. mPFC-insular cortex

What is....c. mPFC-insular cortex?

300

Applying this hormone can potentially rescue certain social deficits in ASD.

a. insulin

b. progesterone

c. oxytocin

What is....c. oxytocin?

300

In the rodent study by Rogers-Carter et al., 2018, experimental rats showed preference for interaction with stressed juveniles and avoidance of stressed adults. This social mechanism is called....

a. social approach

b. social discrimination

c. social competition

What is....b. social discrimination?