Pharmacokinetics and Pharmacodynamics
This organ is the primary site of drug metabolism.
What is the liver?
Review pharmacokinetics process - ADME
This schedule category of controlled substances means the substances have a high potential for abuse that can lead to severe psychological or physical dependence.
What is a schedule II controlled substance?
Know the Controlled Substances - The Comprehensive Drug Abuse Prevention and Central Act - including schedules and nursing considerations.
Albuterol is given to open up bronchioles by stimulating this receptor.
What is Beta2 ?
These are the common side effects of cholinergic medications.
What is SLUDGE?
Salivation, Lacrimation, Urination, Defecation, GI cramps, and Emesis
Convert 5 Tablespoons to teaspoons.
What is 15 teaspoons?
(If you are struggling, you need to look at Chapter 11)
For orally administered drugs, this affects the bioavailability.
What is the first-pass metabolism in the liver?
Review bioavailability
This refers to the use of more medications than is medically necessary. Taking five or more drugs is associated with an increased incidence of adverse drug reactions, geriatric syndromes, and increased mortality.
This medication stimulates alpha2 receptors causing a decrease in blood pressure.
What is clonidine?
These are the common side effects of anticholinergics or cholinergic antagonists.
What are "Dry Can't's"
Can't see, can't pee, can't spit, can't ____
Convert 5 grams to milligrams.
What is 5,000 mg?
(If you are struggling, see Ch. 11)
What is inactive?
In children less than 6 years of age, this should be used to administer oral medication.
What is an oral syringe?
Be familiar with Pediatric Drug Administration
Stimulation of Beta1 receptors will cause these effects.
What are increased heart rate, increased force of contraction, increased renin, and increased blood pressure?
Know Beta 1 and 2
This medication helps to restore the acetylcholine and dopamine imbalance in Parkinson's. It is also used to help control extrapyramidal symptoms of some antipsychotic drugs.
What is benztropine?
Convert 156 pounds to kilograms. (Round to the nearest whole number)
What is 71 kg?
This is the lowest plasma concentration of a drug, and it is drawn just before the next dose of drug regardless of the route of administration.
What is a trough drug level?
These are the six rights of medication administration.
What are:
Right patient, Right drug, Right dose, Right time, Right route, and Right documentation?
Epinephrine can cause this side effect due to the stimulation of Beta2 receptors.
What is hyperglycemia?
This medication treats myasthenia gravis by allowing more acetylcholine to be picked up at the receptor site. Increased ACh increases muscle strength for these patients.
What is pyridostigmine?
Convert 4 cups to ounces.
What is 32 ounces?
(If you are struggling, see Ch. 11)
Drug M has a half-life of 6 hours. A patient takes 500 mg at 9 am. How much drug would remain after 24 hours? (The patient has normal kidney and liver function)
Older adults can have reduced metabolism and excretion of medications causing an increased risk for this.
What is drug toxicity?
This action by epinephrine causes the blood pressure to go up. But watch out, too much of this can lead to digital ischemia and decrease renal perfusion.
What is vasoconstriction?
Cholinergic agonist drugs will have similar effects on the heart rate and blood pressure as adrenergic _________ drugs.
What are adrenergic antagonists drugs?
Convert 4 cups to mL.
What is 960 mL?
(If you are struggling, see Ch. 11 - table)