True or false: The fasciculus cuneatus contains sensory information from the legs
False
100
In which horn are alpha motor neurons found?
The ventral horn
100
Damage to the fasciculus gracilis will cause what deficit?
Loss of fine touch and proprioception to the ipsilateral leg
100
A patient presents with bilateral loss of pain and temperature sensation to the arms and some muscle weakness in both arms. What is the most likely diagnosis?
Syringomeyelia
100
True of false: only 15% of corticospinal tract fibers decussate in the pyramids.
False. 85% of fibers cross here
200
Through what pathway do spinothalamic tract fibers decussate?
Ventral white commissure
200
What in which lamina is Clark's nucleus?
Lamina VII, the intermediate zone
200
What clinical symptoms would you expect from a lesion to the ventral white commissure at T7 only?
No remarkable symptoms
200
True of false: A stroke of the ventral spinal artery would cause bilateral signs of upper motor neuron damage at the level of the stroke and bilateral signs of lower motor neuron damage below the level of the stroke.
False
200
Where are the cell bodies located for axons that travel in the spinothalamic tract?
Dorsal root ganglion
300
From lateral to medial, list the somatotopic organization of spinal segments in the dorsal column (fasiculus cuneatus and fasciculus gracilis).
Cervical, Thoracic, Lumbar, Sacral
300
Which lamina contains the substantia gelatinosa?
Lamina II
300
What clinical symptoms would you expect from a patient with damage to the lateral corticospinal tract at T10?
Spastic paralysis, hyperreflexia, hypertonic, clonus, clasp-knife response, and Babinski sign
300
What disease is characterized by a loss of myelin in the CNS?
Multiple sclerosis
300
Where do the axons that run in fasciculus gracilis and cuneatus terminate?
Gracile nucleus and cuneate nucleus (dorsal column nucleus)
400
Cell bodies from Clark's nucleus project their axons through which tract?
The dorsal spinalcerebellar tract
400
Between which spinal levels is the intermediolateral nucleus found?
T1-L2
400
A patient presents with loss of fine touch and proprioception of the right leg, loss of pain sensation of the left leg and signs of upper motor damage in the right leg. What is the name for the lesion that could produce these symtoms?
Brown-Sequard's Syndrome or hemisection of the spinal cord
400
Poliomyelitis attacks what type of neurons (motor or sensory)? Where are the attacked neurons located?
Ventral horn motor neurons
400
Axons from the ventral corticospinal tract innervate neurons that control what?
Axial muscles
500
In which funiculus is the pontine reticulospinal tract located?
Ventral funiculus
500
To which lamina do lateral division fibers travel? (Hint: there are 3 total)
Laminae I, II, and V
500
A patient is transported to the emergency department following a gun shot wound to the mid back. The bullet is presumed to have entered the spinal cord. He has no patellar reflex in his left leg. Based on this information, what spinal levels are probably injured?
L2, L3, L4
500
What autosomal recessive disease is characterized by spinal muscular atrophy and is caused by a defect of chromosome 5?
Werdnig-Hoffmann disease
500
Where are the third neuron cell bodies of the dorsal columns system. Be specific. Where do their axons terminate? Be specific.
Ventral posterior lateral nucleus of the thalamus. Post-central gyrus (primary somatosensory cortex)