Tissue Repair
Hemostasis
What occurs immediately after an acute injury?
about 5 days after the injury
When do the fibroblasts, epithelial cells and vascular endothelial cells move into the wound to form granulation tissue?
Increased Sedimentation rate
What is a sign of Chronic Inflammation?
thin, clear, yellow or straw colored (proteins)
What is serous exudate?
Blood fills the gap, Coagulation begins and clumping platelets form a loose clot.,
What occurs to stop the bleeding in hemostasis?
Dehiscence or reopening occurs
What happens if the granulation tissue is not strong enough?
Phagocytosis
What is the ingestion of microorganisms, other foreign substances, necrotic cells etc.?
cloudy, pus, cellular debris
What is purulent exudate?
growth factor
What stimulate proliferation and migration of epithelial cells, fibroblasts, and vascular endothelial cells regulate the differentiation of cells?
Erythema, Heat, Edema, Pain
What are the 4 cardinal signs of Acute Inflammation?
irritation of the sensory nerve endings at the site of the initial cell damage and subsequent inflammation
What causes pain and tenderness at the initial site of inflammation?
thin usually clear, yellow, pink tinged or cloudy, occurs with severe inflammation and can cause scarring
What is fibrinous exudate?
within 24 hours of the injury
How soon does tissue repair begin?
decreased function
What is the 5th sign of acute inflammation?
mononuclear cells (monocytes, macrophages)
Which leukocyte arrive later in the process and “clean-up” all the debris (dead cells) that are the result of inflammation?
bright red or bloody (RBCs)
What is sanguineous exudate?
non functional connective tissue
What is fibrous or scar tissue?
inactivate injurious agent, to break down and remove the dead cells and to initiate healing of tissue through the process of phagocytosis
What is the function of the inflammatory reaction?
Develops if underlying cause is not addressed
Injurious agent persists, accumulation of macrophages, lymphocytes and plasma cells
Healing usually without full return of function
What is Chronic Inflammation?
Build up of fluid is a combo of protein, leukocytes, and cellular debris
What is exudate?