STEP 1 Jeopardy

Pharmacology

100

Got LDL? This enzyme is targeted by statins.

HMG-CoA Reductase

200

Certain direct anti-coagulant drugs, such as apixaban, target this coagulation factor

X (or Xa)

300

Is your QT prolonged? Best avoid this class of antibiotics that target DNA-gyrase.

Fluoroquinolones

400

Too much methotrexate? Take this medication, which can rescue patients from its toxic effects

Leucovorin

500

Serotonin Syndrome? No problem! Just use this antidote

Cyproheptadine

Pathology

100

Parkinson's syndrome often causes atrophy of this basal ganglion structure

Substantia Nigra

200

Name that diagnosis: fractures, nephrolithiasis, altered mental status, and abdominal pain

Hypercalcemia (bones, stones, moans and groans)

300

Imatinib can target this specific type of gastro-intestinal cancer

Gastro-intestinal stromal tumor (GIST) [c-kit]

400

This type of leukemia is associated with t(15:17)

Acute pro-myelocytic leukemia

500

Vasculitis associated with c-ANCA

Wegeners (granulomatosis with polyangiitis)

Physiology

100

Take a deep breath; now let it out all the way. This is what you are left within the lungs.

Residual volume.

200

This hormone inhibits the secretion of prolactin

dopamine

300

This electrolyte is needed for co-release for PTH

Magnesium (which is one of the reasons why alcoholics have low calcium)

400

This law of fluid dynamics is the basis for why two IVs are better than one big central line (which is longer)

Poiseuille's law

500

The key determinants of mean arterial blood pressure

MAP = C.O. x SVR + CVP (cardiac output, systemic vascular resistance, and central venous pressure)

Microbiology

100

Bacteria that causes toxic megacolon after receiving antibiotics

C diff

200

Name the diagnosis: an AIDS individual with meningitis, skin lesions, and lots and lots of pigeon exposure

Cryptococcus

300

This organism is associated with hemolytic anemia and maltese cross formations in RBCs

Babesia

400

This parasite is notable for its ability to auto-infect and cause hyperinfections

Strongyloides

500

An arthropod-borne virus that causes extreme joint pains for travelers to the Caribbean

Chikagunya

Potpourri

100

Name the diagnosis: anion gap of 18, arterial pH 7.25, and glucose of 400

DKA

200

Thoracic outlet syndrome can be due to when the brachial plexus is impinged by this group of muscles

scalenes

300

This vitamin is a co-factor for folate production

B12

400

All clotting factors are made in the liver except....

Factor VIII

500

The most common cause of pulmonary arterial hypertension world-wide

Schistosoma