Step 2CK Review (part 2)

Side effect profiles

100

This drug, used for the treatment of dyslipidemia, can cause diffuse musculoskeletal pain and even rhabdomyolysis

Statins

200

This drug, used in the treatment of osteoporosis, can cause atypical fractures of the long bones, erosive esophagitis and osteonecrosis of the hip

Bisphosphonates

300

When working up a case of peripheral edema, be sure to rule out the use of this class of medication, which can be used to treat hypertension, amongst other things

Calcium channel blockers

400

Chronic use of this medication can have many different side effects, but gingival hypertrophy is a common one

Phenytoin

500

This medication, used as a steroid-sparing agent, typically for rheumatoid arthritis, can cause hepatic fibrosis as well as pulmonary fibrosis

Methotrexate

Eponyms

100

The scoring criteria is used to decide on help risk stratify patients who present with symptoms that may suggest venous thromboembolism (DVT or PE)

Wells Criteria

200

This scoring criteria is used to help risk stratify patients who you are concerned may have bacterial endocarditis

Duke's Criteria

300

This AIDS-defining skin condition is of viral etiology

Kaposi Sarcoma

400

This ‘effect’ can cause morning hyperglycemia as a result of low blood sugars during the night that trigger counter-regulatory hormone release

Somogyi effect

500

This syndrome is the result of excessive secretion of ACTH from the pituitary gland

Cushing Syndrome

Secondary Consequences

100

This progressive neurological condition can occur after an infectious diarrhea such as Campylobacter but also after routine vaccination for influenza. It is reversible if caught early, but if not can lead to diaphragmatic paralysis and death

Guillain Barre Syndrome (GBS)

200

This condition is associated with ulcerative colitis (IBD), though it can also be spontaneous. It leads to progressive destruction of the biliary system both inside and outside the liver

Primary Sclerosing Cholnagitis (PSC)

300

This gastric lymphoma is easily preventable and treatable if the underlying infectious cause is dealt with

MALT lymphoma

400

This systemic condition is typically secondary to multiple myeloma or chronic inflammatory conditions such as IBD, rheumatoid arthritis or FMF

Amyloidosis

500

Acute renal failure and glomerulonephritis can be a result of this bacterial infection of the pharynx

Group A strep (GAS) or Strep. pyogenes

Bugs

100

This is the most common cause of community acquired bacterial pneumonia

Strep. pneumo

200

This is the most common cause of meningitis in newborns

Group B strep (GBS)

300

A CD4 count less than 200 can increase the risk of this AIDS defining parasitic infection

Toxoplasmosis

400

This bacterial can lead to infectious arthritis, particular in patients who are asplenic

Salmonella

500

Longstanding infections with this STI can lead malfunction of the dorsal column

Syphilis

It's Not Lupus

100

This antibody is nearly 100% sensitive. In other words, if it is normal, you do not likely have lupus

ANA

200

Drugs like penicillamine or hydralazine can lead to a secondary lupus syndrome that characteristically that typically show anti-THIS antibodies

Anti-Histone antibodies

300

Often associated with lupus, patients with this condition are prone to early pregnancy losses

APLA

400

THIS neonatal complication can be seen in patients who are Anti-Ro positive

congenital heart block

500

Patient who have lupus or APLA, can develop THIS non-infectious endocarditis

Libman Sacks endocarditis