Carotid disease
The first carotid endarterectomy procedure was performed when and by whom.
DeBakey
1953
This neuromuscular neurologist known for his early work on Guillain Barre syndrome was the founder of the Calgary Stroke Program.
Tom Feasby
These two common single gene variants are associated with a prothrombotic states, typically venous thrombosis including cerebral venous thrombosis
Factor V Leiden (leading to activated protein C resistance)
Prothrombin gene polymorphism
This common intracellular bacterium may be found in carotid endarterectomy specimens using in situ immunostaining.
Chlamydia pneumoniae, Helicobacter pylori
This is the most important risk factor (quantitatively) for stroke.
Hypertension
The first carotid endarterectomy was performed on the which side?
Left
The first academic leader of the Calgary Stroke program was Alastair Buchan, who later became the dean of University of Oxford Medical school. His most important rodent experiments in neuroprotection identified the essential confounding role of this factor.
Temperature
Elevated Russell viper venom time indicates this procoagulant is present.
Lupus anticoagulant.
Vaccination against this common virus is associated with a reduction in stroke risk by about 25%
Influenza A
Hyperhomocysteinemia is a weak risk factor for atherosclerosis and stroke is commonly caused by deficiency of this vitamin.
Cobalamin (Vitamin B12)
This neuroradiologist unlocked the patient selection for CEA by developing a reliable and pragmatic way to measure carotid artery stenosis. Bonus: what was the method?
Alan Fox
A person (we have at least 3 in our group) who speaks Malayalam is called this.
Maloo
An elevated PTT which normalizes with a 50:50 mix indicates this condition.
Factor deficiency (eg. Hemophilia)
The virus is associated with the development of antibodies that can result in thrombosis in response to cold exposure.
Hepatitis B, Hepatitis C
Miller-Fisher conducted detailed pathological investigation of small penetrating arteries associated with lacunar stroke and found this cause most commonly.
Among all CEA and CAS procedures performed annually in the United States, the proportion of patients that are asymptomatic.
90%
This experienced clinician pushed the first dose of IV alteplase for stroke in Canada on April 1st, 1996?
Nancy Newcommon
Among epithelial cancers, this broad type of cancer is more commonly associated with a hypercoagulable state.
Adenocarcinoma, particularly mucinous adenocarcinoma. Squamous carcinoma are rarely associated with thrombosis.
Stroke due to infective endocarditis cause by Streptococcus gallolyticus (Strep. bovis) requires this investigation.
Colonoscopy
Osteogenesis imperfecta and Turner’s syndrome, among others, are associated with this cerebrovascular condition.
Extracranial artery dissection.
The number needed to treat to prevent one stroke, if CEA is performed within 2 weeks of symptom onset.
NNT = 3
ARR = 32%
These three brothers, Doc, BJ and Don founded Bow Valley Industries, were original Calgary Flames owners bringing the team from Calgary to Atlanta and were essential to this critical piece of infrastructure at FMC.
Seaman MR Research Centre
A severe deficiency of this enzyme or autoimmune inhibition of this enzyme is associated with thrombotic thrombocytopenic purpura.
ADAMTS13
Large vessel ectasia vasculopathy and cognitive impairment with cerebral multinucleated giant cells is pathognomonic of this virus.
HIV
This type of leukemia with PML:RARA fusion (formerly called M3 type) is particularly associated with acute ICH.
Acute promyelocytic leukemia