EMVISION
Unlike CT scanners, the Emu™ device avoids this risk while still detecting intracranial hemorrhage.
What is radiation exposure?
Weakness or paralysis on one side of the body occurs when a stroke damages this brain structure that controls voluntary movement
What is the primary motor cortex?
Rather than a pharmacologic therapy, this form of non-invasive neurostimulation is being tested as a potential treatment for acute ischemic stroke.
What is cathodal high-definition transcranial direct current stimulation (HD-C-tDCS)?
The Ceribell STROKE trial is evaluating whether EEG technology can help differentiate between these types of acute neurological events.
What are large vessel occlusion (LVO), non-LVO ischemic stroke, intracerebral hemorrhage (ICH), transient ischemic attack (TIA), and stroke mimics?
This attending is founder of the Mobile Stroke Unit and is the PI for multiple clinical trials we work on.
What is Dr. Nour
The EMVision trial studies a portable device that uses this technology to assess brain inju
What is ultra–high frequency radiofrequency scanning?
A patient presents with vertigo, ataxia, and difficulty coordinating limb movements. The stroke most likely involves this brain region responsible for balance and coordination.
What is the cerebellum?
To be eligible, participants must have this type of vascular finding and corresponding imaging evidence of viable tissue.
What is a cortical vessel occlusion and a salvageable ischemic penumbra on perfusion imaging?
A patient cannot be enrolled if the treating team believes that applying the EEG headband would cause this.
What is interfere with clinical assessment or treatment?
This attending did their vascular neurology fellowship at UCLA and is a PI for one of our trials.
What is Dr. Bahr
The goal of EMVision is to improve this aspect of stroke care in emergency settings.
What is rapid triage and prehospital stroke detection?
A stroke affecting the superior division of the left MCA would most likely impair this specific cortical area, leading to non-fluent, effortful speech with intact comprehension.
What is Broca’s area?
The rationale for HD-C-tDCS in acute stroke is to modulate neuronal excitability to produce this vascular effect.
What is enhancement of collateral blood flow to ischemic but salvageable brain tissue?
EEG must be recorded before multimodal imaging or within this time window after imaging completion.
What is 30 minutes?
This attending is famous for wanting all of the blinds closed during neurorounds and is the director of the Neurovascular Imaging Research Core at UCLA
What is Dr. Liebeskind
To qualify for the study, patients must present with suspected stroke within this time window from symptom onset.
What is within 12 hours?
A patient develops contralateral hemianopia, visual agnosia, and mild memory impairment after a stroke. The lesion most likely involves this artery and this cortical region of the brain.
What are the posterior cerebral artery (PCA) and the occipital lobe (with possible extension to the medial temporal lobe)?
TESSERACT-2 is designed to test HD-C-tDCS both in isolation and in conjunction with this class of stroke treatment.
What are intravenous thrombolytics (such as alteplase or tenecteplase)?
Ceribell trial’s endpoint is not diagnostic confirmation but correlation of EEG signatures with these specific vascular and mimic categories. Name at least three.
What are LVO, non-LVO ischemic stroke, intracerebral hemorrhage (ICH), transient ischemic attack (TIA), and stroke mimics?
I’m a behavioral, cognitive, and vascular neurologist whose research transformed acute stroke care. I led the FAST-MAG and SWIFT PRIME trials, chaired the AHA Stroke Council, and serve as Associate Editor at JAMA.
What is Dr. Saver
A 64-year-old with a pacemaker presents 6 hours after onset. They are eligible for CT but not MRI. Can they be enrolled in EMVision?
What is yes — pacemakers are located in the chest, not the head or neck, so they do not violate the exclusion for implanted electro-stimulating devices near the scan area?
After a minor head injury, a patient awakens with sudden left-sided numbness and clumsiness in the face, arm, and leg, but no facial droop, aphasia, or visual field loss. Imaging reveals NO intracranial hemorrhage. What is the diagnosis?
What is thalamic stroke?
A 76-year-old patient presents 3 hours after onset with an M1 occlusion, fluctuating consciousness, and perfusion imaging showing a 25 mL core and 90 mL penumbra. They received IV tPA and have atrial fibrillation on anticoagulation reversal. Can they be enrolled in TESSERACT-2?
What is yes — they meet criteria with cortical vessel occlusion and salvageable penumbra; concurrent thrombolytic therapy is permitted, and HD-C-tDCS can be delivered to enhance collateral flow and penumbral salvage?
Before randomization, all subjects undergo baseline imaging. List two radiographic findings that immediately exclude enrollment.
What are (1) intracranial hemorrhage or (2) lack of salvageable penumbra with mismatch ratio ≥ 1.2 on perfusion CT or MR
This attending is a Walter Brutsch Endowed Chair and Professor of Neurology at UCLA, directing both the Comprehensive Stroke and Vascular Neurology Center and the TeleStroke Program. Their work spans simulation medicine, pediatric stroke, and stroke prevention, and have been recognized with the AAN Clinical Research Fellowship and AHA Bugher Foundation Awards.
What is Dr. Sharma