Circadian Rhythms
Brain and Memory
Effects of Sleep Deprivation
Long-Term Consequences
100

This chemical waste product builds up in your brain throughout the day, making you feel tired.

What is adenosine?

100

This neurotransmitter spikes after an all‑nighter, causing a temporary sense of euphoria.

What is dopamine?

100

This stimulant blocks adenosine from binding to receptors, helping you stay awake.

What is caffeine?

100

This mental health condition becomes more likely when sleep schedules are irregular. 

What is depression?

200

This hormone, released by the pineal gland, rises about two hours before bedtime to prepare your body for sleep.

What is melatonin?

200

This part of the brain, responsible for decision‑making and self‑control, functions poorly without sleep.

What is the prefrontal cortex?

200

Staying awake for 19 hours impairs your coordination as much as this activity.

What is drinking alcohol?

200

College students with consistent sleep schedules tend to have higher scores in this academic measure.

What is GPA?

300

This calming neurotransmitter slows brain activity as bedtime approaches.

What is GABA?

300

This emotional center of the brain becomes overactive when you’re sleep‑deprived.

What is the amygdala?

300

This drop in your body occurs before sleep and helps your brain cool down.

What is core body temperature?

300

Regularly getting less than seven hours of sleep increases your risk for this blood‑sugar‑related disease.

What is diabetes?

400

This brain structure acts as your body’s internal clock, responding to light and controlling sleep‑wake cycles.

What is the suprachiasmatic nucleus?

400

This brain region temporarily stores new information while you study.

What is the hippocampus?

400

This type of thinking suffers most during an all‑nighter, making essay writing difficult.

What is problem‑solving or making connections between ideas?

400

Chronic sleep loss raises your risk for this major cardiovascular event.

What is a stroke?

500

These brief, uncontrollable episodes of sleep occur when you’re severely sleep‑deprived.

What are microsleeps?

500

During sleep, memories are transferred from the hippocampus to this long‑term storage area.

What is the neocortex?

500

This “second wind” feeling happens when melatonin production stops at sunrise.

What is a temporary alertness boost?

500

This phrase reminds you that learning takes time and can’t be rushed in one night.

What is “Rome wasn’t built in a day”?