Brain Effects
Body Effects
Myth vs. Fact
Effects of Substance Use
Tolerance, Dependence, & Withdrawal
100

Which part of the brain helps with decision-making and impulse control?

The prefrontal cortex

100

Which organ processes most alcohol in the body?

The liver. 

100

Coffee can instantly "sober up" someone who is intoxicated by alcohol.

Myth (false)
100

What is one common short-term and one common long-term effect of alcohol?

Short-term: Reduced coordination, Slower reaction time, Impaired judgement

Long-term: Liver disease, Heart problems, Memory problems, Increased cancer risk

100

What does "tolerance" mean?

Needing more of a substance to achieve the same effect.

200

What neurotransmitter is commonly associated with pleasure and reward? 

Dopamine.

200

What body system is slowed by opioids?

The respiratory system (breathing). 

200

A person can become dependent on a substance without intending to.

True (fact)

200

What stimulant effect might occur after using cocain or methamphetamine?

Increased energy

Increased heart rate

Increased alertness

increased confidence

200

What is withdrawal? 

Physical and/or psychological symptoms that occur when use is reduced or stopped after regular use.

300

Why can repeated substance use make natural rewards (hobbies, relationships, goals, etc.) feel less satisfying?

The brain adapts to high dopamine levels, making everyday activities feel less rewarding.

300

Name two body systems that can be affected by nictoine.

Cardiovascular system (heart)

Respiratory system (lungs)

Nervous system (movement and thoughts)

300

Addiction affects brain function, not just behavior

True (fact)

300

Why might driving become more dangerous after using cannabis?

Slower reaction time, reduced attention, altered perception, and impaired coordination.

300

Name three common withdrawal symptoms.

Anxiety, sweating, nausea, shaking, insomnia, irritability, etc.

400

Which two brain areas work together when someone experiences a strong craving: one invovled in emotions and one involved in memory?

The amygdala and hippocampus. 

The amygdala attaches emotional significance to experiences, while the hippocampus stores memories associated with substance use. Together they can trigger cravings when someone encounters reminders of past use.

400

Why are stimulants such as cocaine and methamphetamine particularly risky for the heart?

They can increase heart rate, blood pressure, and strain on the cardiovascular system, increasing the risk of heart attack, stroke, and abnormal heart rhythms.


Many young adults assume heart problems only happen later in life, but stimulants can create serious cardiovascular risks at any age  

400

If someone has never experienced withdrawal symptoms, they cannot have a substance use problem.

Myth (false)

Substance use problems exist on a spectrum. Some people may experience significant consequences and loss of control before developing physical dependence.

400

A substance may make someone feel more relaxed in the short term but increase anxiety and depression symptoms over time. Which commonly used substances can have this effect?

Alcohol, cannabis, opioids, nicotine, and other substances can contribute to this pattern.


The immediate effects of a substance may differ significantly from its long-term impact on mental health.  

400

What is the difference between tolerance and dependence?

Tolerance: The body adapts, requiring more of a substance for the same effect.

Dependence: The body has adapted to the substance and experiences withdrawal symptoms when use stops.


A person can develop tolerance before dependence, and neither automatically means addiction.