True or false: psychosocial treatments for substance use disorders are equally efficacious
True
The first 12-step program
AA
___ is a μ opioid receptor full agonist
Methadone
Induced hangover-like effects by inhibiting the enzyme aldehyde dehydrogenase
Disulfiram (bonus: what line treatment is it?)
Animal sedative being increasingly abused and mixed with fentanyl
Xylazine (tranq)
Bonus question: what medication is it similar to?
A technique used to promote sobriety by finding triggers/stressors for substance use and avoiding those situations
Relapse provention
True or false: motivational enhancement therapy (MET) and cognitive behavioral therapy (CBT) are more effective than 12 step programs
False, 12-step programs are slightly more effective at promoting continued abstinence/sobriety
FDA approved medication for Gambling Disorder
None
But dopamine agonists, naltrexone, lithium, antidepressants, and antipsychotics have been used
Receptor target for treatment of T2DM, obesity, and potentially addiction through hypothesized mediation of dopamine pathways.
GLP-1 receptor (medications are receptor agonists)
Leading global cause of preventable death
Tobacco use
A therapeutic approach aimed at helping individuals identify and resolve ambivalence regarding alcohol and other drug use
Motivational Enhancement Therapy (MET), ie Motivational Interviewing
This psychotherapist may have inspired a patient to start AA around 1935
Carl Jung
___% of VA patients receive medication treatment for alcohol use disorder (closest answer wins)
7-11%
FDA approved medication for stimulant use disorder
None
What percentage of drug overdose deaths in the US in 2021 are associated with opioids? (closest answer wins)
75%
Average member sobriety in AA is ___ years (closest answer wins)
10
Operant conditioning technique used to promote continued abstinence, by providing small rewards/reinforcers
Contingency management
___ is a μ opioid receptor partial agonist
Buprenorphine
___ is a μ opioid receptor antagonist
Naltrexone
Under conditions for further study in DSM-5: in utero exposure to what substance?
Alcohol
(Neurobehavioral disorder associated with prenatal alcohol exposure)
At __ AA meetings, non-alcoholics are welcome
Open
As of 2018, ___ number of weekly NA meetings occur in 144 countries (closest answer wins)
70,000
Suboxone has ___% bioavailability (closest answer wins)
30%
Hepatically safe medication for AUD and theorized MOA
Acamprosate
NMDA receptor antagonist and positive allosteric modulator of GABA-A receptors.
From 1999 to 2021, drug related deaths have increased by what percentage? (closest answer wins)
780%