Types of Substances
Effects and Risks
Addiction and the Brain
Recovery Facts
Laws and Social Impact
100

This legal stimulant is the most widely used psychoactive substance in the world.

What is caffeine?

100

This short-term effect of alcohol can impair judgment and coordination.

What is intoxication?

100

This brain chemical, linked to pleasure and reward, is released in large amounts by addictive substances.

What is dopamine?

100

Sudden changes in friends, mood, or school performance could be signs of this.

What is substance use?

100

This government agency regulates legal drugs and approves medications in the U.S.

What is the FDA (Food and Drug Administration)?

200

This commonly used substance can be smoked, vaped, or chewed and contains nicotine.

What is tobacco?

200

Long-term use of methamphetamine can cause this dental condition.

What is "meth mouth"?

200

This part of the brain, which helps with decision-making, can be affected by long-term drug use.

What is the prefrontal cortex?

200

This type of drug test can detect the presence of substances in a person’s system.

What is a urine test?

200

This term describes the illegal sale or distribution of drugs.

What is drug trafficking?

300

Often prescribed for pain, this class of drugs includes oxycodone and morphine.

What are opioids?

300

This term describes the need for more of a drug to get the same effect.

What is tolerance?

300

This term describes when someone can't stop using a substance despite negative consequences.

What is addiction?

300

Talking openly, setting clear rules, and staying involved in a teen’s life are part of this parenting strategy.

What is prevention?

300

This federal law established harsh penalties for drug offenses in the 1980s.

What is the Controlled Substances Act (or "War on Drugs" legislation)?

400

This hallucinogen, sometimes called "acid," became popular in the 1960s.

What is LSD?

400

This term describes the physical and mental symptoms that occur when stopping a drug.

What is withdrawal?

400

This treatment approach combines behavioral therapy and medications for addiction recovery.

What is medication-assisted treatment (MAT)?

400

This legal drinking age is enforced in the United States.

What is 21?

400

This program, often remembered by its slogan "Just Say No," was part of a 1980s drug prevention campaign.

What is D.A.R.E. (Drug Abuse Resistance Education)?

500

This substance, also known as MDMA, is often used recreationally at parties or raves.

What is ecstasy?

500

Overuse of alcohol over time can lead to this serious liver disease.

What is cirrhosis?

500

This mental health condition often occurs alongside substance use disorders.

What is a co-occurring disorder (or dual diagnosis)?

500

This national hotline offers free and confidential help for people with substance use issues.

What is the SAMHSA helpline (1-800-662-HELP)?

500

Some states have legalized this drug for recreational and/or medical use, while it remains illegal under federal law.

What is marijuana (or cannabis)?