Which neural pathway in the brain is linked to addiction/dependence.
Reward pathway-
What is TOLERANCE.
When more of the drug is nessecary to create the same effects in the body after repeated use of the drug.
What is the common start point for Heroin addicts.
prescription opiods
Which synthetic opiod is responsiblie for increase of overdose deaths
Fentanyl
which neruon does opiates inhibit/Block
GABA.
What is HOMEOSTASIS.
The bodies natural drive to maintain normal conditions and sytems in the body.
Name the 3 key players the video states influences Opiod Use Disorder.
Tolerance
Drug Liking
Dependence and withdrawal
Name the drugs being laced/cut with fentanyl
Cocaine, Meth, herion, oxycodone.
Which chemical is believed to be responsible for tolerance.
cAMP.- Adenylyl Cyclase
Name 3 opiate withdrawal symptoms.
Rapid heart rate, Rapid breathing, Jitteriness, insomnia, anxiety, panic, stress, excessive sweating, large pupils, diarehha, feelings of discomfort.
Name 2 enviormental risk factors for addiction.
Peer group influence
family and social instability
Drug availability
low socioeconomic status
How can you reduce risks of over perscriptions with your physican?
Share your medical history including current/past addiction disorder. Communicate with your doctor.
How does the nurons try to compensate for the blocking from opiates.
Overreact- Over-reactive neurons- create more then normal to compenstate
What happens during an opiate overdose that makes it so deadly.
respirtory suppression. You stop breathing
Can you name 2 of the areas used for diagnosing opiate use disorder?
Loss of control, risky opiates use, social problems and pharmacalogical problems
When drugs are laced/cut with fentanyl this process increases what?
risk of overdose & death
Which chemical floods the brain when opiates block GABA
Dopamine.
What drug can reverse an opiate overdose.
Naloxone
Name 2 genetic risk factors for addiction.
Mutation in reward and stress pathways
Altered Drug metabolism
Brain Structure
Receptor structure and density
Name 2 medications that assist in opiod use disorder treatment.
Methadone, Suboxone Bupurnorphrine