Medications
This medication disrupts alcohol metabolism by causing irreversible inhibition of the enzyme acetaldehyde dehydrogenase and increasing acetaldehyde levels
What is Disulfiram
Mesolimbic part of the brain causes a release from the nucleus accumbens and is associated with reward and reinforcement
Dopamine
Criteria for SUD has not been met for at least 3 months but less than 12 months
What is early remission
This act created in 2008 required any practitioner issuing a prescription for a controlled substance to conduct an in-person medical evaluation and in-person exam at least once every 24 months.
What is the Ryan Haight Act
Slurred speech,Incoordination, Unsteady gait, Nystagmus, Impairment in cognition (e.g., attention, memory). Paradoxical reactions are possible
What is Sedative, Hypnotic or Anxiolytic Use
After recent cessation of alcohol, a patient presenting with mental confusion, oculomotor disturbance, dysarthria & Ataxia should be treated with what?
What is Thiamine
This neurotransmitter is the brain’s major inhibitory neurotransmitter
GABA
A markedly diminished effect with continued use
what is tolerance
In the 1970s this act Placement is based upon the substance’s- accepted medical use, potential for abuse & safety or dependence liability
What is the controlled substance act
Tachycardia, Dry mouth, Euphoria, Conjunctival injection, Delayed reaction time, Short term memory loss
What is Cannabis Intoxication
This medication is thought to reduce the mesolimbic reward system and has shown benefit in reducing cravings
What is Naltrexone
Benzodiazepines (BZDs) and barbiturates are gamma-aminobutyric acid type A (GABA-A) receptor agonists. Benzodiazepines work by
increase ion channel opening frequency
Maladaptive behavioral change, with psychological and cognitive concomitants, that is due to the cessation of, or reduction in, prolonged substance use
What is withdrawal
Encompasses the understanding that traditional law enforcement approaches or those that require complete abstinence do not decrease demand, use, or negative health consequences of substance use
What is harm reduction
Increased Blood Pressure, Increased Heart Rate, Rhinorrhea, Bruxism, Hyperactivity, Perspiration, Chills, Poor appetite
What is Cocaine intoxication
Which medication is ideal for those with hepatic impairment and seeking MAT from alcohol
Campral
These substances increasing synaptic release of the monoamines while; these substances increases synaptic levels of monoamines by inhibiting uptake
What is Amphetamines and Cocaine
Following cessation of use of a hallucinogen, the reexperiencing of one or more of the perceptual symptoms that were experienced while intoxicated with the hallucinogen
Hallucinogen Persisting Perception Disorder
These substances have the potential to be misused and to cause dependence usually after >4 months
What are benzodiazepines, Z-drugs, and barbiturates
Drowsiness, Slurred speech, Impairment in attention or memory, Pupillary constriction
What is Opioid intoxication
This drug inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex
What is Flumazenil
Mechanistically, classical hallucinogens have agonist or partial agonist activity at what receptor
5-HT2A receptors
Moderate severity of Substance Use is based on the presence of how many symptoms
what is 4-5
Polymorphisms of genes resulting flushed face & palpitations for the alcohol-metabolizing enzymes alcohol are most often seen in what population?
Asians - Gene variations are seen in as many as 40% of Japanese, Chinese, Korean, and related groups worldwide
Dilated pupils, Loss of depth perception, xerostomia, Increased Heart Rate, Increased Blood Pressure
What is Hallucinogen Intoxication