Pharmacology
Medical Complications
Clinical Knowledge
Toxidromes and Withdrawal
100

Given by injection or nasal inhalation, this drug can reverse opioid overdose

What is naloxone?

100

This practice may lead to infective endocarditis, hepatitis C, HIV, and skin abscesses.

What is intravenous drug use?

100

Decongestants like pseudoephedrine can produce this false positive result on tox screen.

What is amphetamine?

100

Miosis, respiratory depression, depressed mental status, and constipation are symptoms of intoxication with this substance category.

What are opioids?

200

Varenicline and bupropion have been shown to be effective in reduction of use of this substance

What is  tobacco (or nicotine)?

200

Wernicke's encephalopathy and Korsakoff Syndrome are associated with a vitamin deficiency commonly seen in this substance use disorder.

What is alcohol use disorder?

200

Neurotransmitter enhanced specifically in alcohol and benzodiazepine intoxication.

What is GABA?

200

Withdrawal from this substance can lead to seizures, delirium, hallucinosis, and death from autonomic hyperactivity?

What is alcohol (or benzodiazepines)?

300

In those who heavily use alcohol, this medication that acts as an opioid receptor antagonist has been shown to reduce cravings.

What is naltrexone?

300

Myocardial infarction and stroke are feared acute complications of the use of this substance.

What is cocaine?

300

A urine drug test positive for this substance should never be considered a false positive.

What is cocaine?

300

Acute intoxication with this synthetic drug often increases blood pressure, pulse, respiratory rate, and temperature.

What is methamphetamine?

400

Opioid agonist given only in federally licensed treatment centers that has been shown to decrease mortality in people with opioid use disorder

What is methadone?

400

Hematologic complications of heavy use of this substance include macrocytosis and thrombocytopenia

What is alcohol?

400

Name one substance use disorder for which treatment with medications has been shown to be clearly superior to therapy and counseling alone.

What is opioid use disorder or tobacco use disorder?

400

Withdrawal from this substance can involve sweating, nausea, yawning, abdominal cramping, and anxiety--but is typically not life-threatening

What are opioids?

500

Seizures associated with these 2 substances are not an indication to begin anti-epileptic treatment.

What are alcohol and benzodiazepines?

500

A common adulterant in heroin that is associated with increased risk of overdose and yields a negative result on a standard urine tox screen.

What is fentanyl?

500

Three important non-physician members of an effective treatment team for substance use disorders?

What are (include 3) peer recovery coach, social worker, case manager, nurse, pharmacist, counselor, therapist, psychologist?

500

Irritability, anxiety, worsened sleep, and worsened mood without vital sign changes or GI upset are symptoms of withdrawal from this substance.

What is cannabis (marijuana)?