Neuroimaging Techniques
This technique measures the magnetic fields produced by neuronal electrical activity.
What is MEG (Magnetoencephalography)?
This ion enters the neuron during depolarization.
What is sodium (Na+)?
Parkinson’s disease is primarily associated with the degeneration of neurons in this structure.
What is the substantia nigra?
This neurotransmitter is critical for the "reward" signal and motor control.
What is dopamine?
Region associated with motor planning, located just anterior to the central sulcus.
What is the premotor cortex?
Functional MRI primarily detects changes in this blood-related signal.
What is the BOLD signal (Blood-Oxygen-Level Dependent signal)?
This protein, when misfolded, is implicated in Alzheimer's disease plaques.
What is beta-amyloid?
In epilepsy, this brain imaging technique is commonly used to localize seizure foci.
What is EEG?
Drug-induced long-term changes in synaptic strength are referred to as this.
What is neuroplasticity (or synaptic plasticity)?
Small but mighty, this structure coordinates fine motor control and balance.
What is the cerebellum?
PET imaging often uses radioligands that bind to these brain targets.
What are neurotransmitter receptors (or proteins/enzymes)?
Synapse elimination during adolescence is known as this.
What is synaptic pruning?
This monoamine hypothesis is associated with depression
What is the serotonin hypothesis?
This neurotransmitter is found in high concentration at the neuromuscular junction.
What is acetylcholine?
This region in the limbic system is critical for forming new memories.
What is the hippocampus?
This imaging method is best known for visualizing white matter tracts.
What is Diffusion Tensor Imaging (DTI)?
The glial cell responsible for myelination in the central nervous system.
What is the oligodendrocyte?
This disorder is characterized by progressive atrophy of frontal and temporal lobes.
What is frontotemporal dementia (FTD)?
Benzodiazepines act on this type of receptor.
What is the GABA-A receptor?
This deep brain structure is involved in both movement and reward.
What is the basal ganglia?
This method allows recording of brain activity with single-cell resolution in behaving animals.
What is two-photon calcium imaging?
This receptor type is involved in long-term potentiation and requires depolarization and glutamate to activate.
What is the NMDA receptor?
A surgical treatment for severe depression or Parkinson’s involving implanted electrodes.
What is deep brain stimulation (DBS)?
This NMDA receptor antagonist is used as an anesthetic and antidepressant.
What is ketamine?
Region implicated in speech production, typically in the left hemisphere.
What is Broca’s area?