Sepsis Showdown
Shock Talk
Vital Gone Wild
Organ Failure Frenzy
MODS Mayhem
Treat It or Tank It
Final Jeopardy: Sepsis or Something Else
All or Nothing: The MODS Cascade
100

This early sign of sepsis often appears before hypotension.

What is tachycardia?

100

This type of shock is caused by severe fluid loss.

What is hypovolemic shock?

100

Narrow pulse pressure is commonly seen in this type of shock.

What is hypovolemic shock?

100

Decreased urine output indicates failure of this organ.

What are the kidneys?

100

MODS most commonly develops as a progression of this condition.

What is sepsis or septic shock?

100

This is the first-line fluid for most shock states.

What is normal saline or LR?

100

A patient has a lactate of 4 mmol/L, MAP of 58 despite fluids, warm flushed skin, and bounding pulses. Explain why this is septic shock and not cardiogenic or hypovolemic shock.

What is...

  • Warm flushed skin and bounding pulses indicate distributive vasodilation, not fluid loss or pump failure.
  • Lactate > 4 and MAP < 65 despite fluids meet criteria for septic shock.
  • Cardiogenic shock would show cool, clammy skin and signs of pump failure.
  • Hypovolemic shock would show narrow pulse pressure and cold extremities.
100

Explain how septic shock leads to MODS by describing the sequence of perfusion changes, inflammatory responses, and the first organ system typically affected.

What is...

  • Septic shock triggers massive vasodilation and capillary leak, causing severe hypoperfusion.
  • The body releases pro‑inflammatory cytokines, damaging the endothelium and worsening oxygen delivery.
  • Microthrombi form, further reducing perfusion to vital organs.
  • The lungs are usually the first organ to fail, often developing ARDS due to increased capillary permeability and inflammatory injury.
  • As perfusion worsens, additional organs—kidneys, liver, CNS—begin to fail, resulting in MODS.
200

A lactate level above this value indicates tissue hypoperfusion.

What is > 2 mmol/L?

200

This shock results from pump failure of the heart.

What is cardiogenic shock?

200

Bradycardia is uniquely associated with this shock type.

What is neurogenic shock?

200

Confusion and agitation indicate dysfunction of this organ system.

What is the central nervous system?

200

The first organ system to show dysfunction in MODS is often this one.

What are the lungs?

200

This medication class is used to increase blood pressure in septic shock.

What are vasopressors?

300

This stage of sepsis includes hypotension that persists despite fluid resuscitation.

What is septic shock?

300

Tension pneumothorax and cardiac tamponade cause this type of shock.

What is obstructive shock?

300

Widened pulse pressure and bounding pulses may appear in this early shock state.

What is early septic shock?

300

Elevated bilirubin and jaundice indicate failure of this organ.

What is the liver?

300

This scoring tool helps evaluate organ dysfunction severity in MODS.

What is the SOFA score?

300

Epinephrine is the first-line treatment for this shock type.

What is anaphylactic shock?

400

This is the minimum amount of fluid recommended early in sepsis resuscitation to improve perfusion.

What is 30 mL/kg of IV crystalloids?

400

Warm, flushed skin is most commonly seen in this shock type.

What is early septic shock?

400

This shock type often presents with severe hypotension and wheezing.

What is anaphylactic shock?

400

ARDS is a severe complication involving this organ system.

What are the lungs?

400

In MODS, this electrolyte imbalance is common due to kidney failure.

What is hyperkalemia?

400

Needle decompression treats this life-threatening cause of obstructive shock.

What is tension pneumothorax?

500

Name two hallmark signs of septic shock.

What are persistent hypotension and elevated lactate?

500

This shock is caused by loss of sympathetic tone after spinal cord injury.

What is neurogenic shock?

500

Cool, clammy skin is a hallmark of all shock types except this one.

What is neurogenic or early septic shock?

500

MODS stands for this.

What is multiple organ dysfunction syndrome?

500

Name two priority interventions to prevent progression to MODS.

What are early antibiotics and aggressive fluid resuscitation?

500

This is the recommended time frame to administer antibiotics in suspected sepsis.

What is within 1 hour?