Choose That Channel
Ions Ions and Ions
Let's Talk About Synapses
100

Which ligand channel closes the slowest?

Which closes the fastest?

Slowest - Metabotropic

Fastest - Ionotropic

Bonus - Why does ____ channel stay open longer?

100

____ ion enters the axon terminal, causing the vesicles to begin emptying their contents into the synapse

Ca2+

Bonus +100 - what does the calcium bind to?

100

What are the two main types of synapses found in the human nervous system?

Chemical and electrical

200

What channel(s) can cause ions to flow?

Always voltage gated channels and ionotropic while sometimes metabotropic

200

When does sodium stop entering the cell?

At the peak of the action potential

200

Which type of synaptic transmission is more common?

Most synaptic transmission in the mature human nervous system is chemical

300

What channel(s) is/are located in the axon, axon hillock, and axon terminal?

Voltage gated

300

What is the relative concentration of ions inside and outside the neuron before the action potential?

More potassium inside. More sodium outside. More chloride outside 

300

Cells connected by gap junctions are said to be _____

electrically coupled

400

What causes each channel to open?

voltage gated / metabotropic / ionotropic

change in membrane potential / ligand / ligand

400

If __ channel is opened, an EPSP occurs. 

If __ channel is opened, an IPSP occurs. 

Na+

K+

400

What separates the presynaptic and postsynaptic membranes at chemical synapses?

synaptic cleft

500

Which channel is responsible for the beginning of an action potential?

Voltage gated sodium channels

500

Which ion is responsible for the hyper polarization following an action potential?

The extra potassium located outside the cell

500

In how many directions may an electrical synapse travel? A chemical synapse?

Unlike the vast majority of chemical synapses, electrical synapses are bidirectional