BCR/TCR counterparts
These proteins, found on traditional T cells, are the counterparts to the BCR heavy and light chains
What are beta and alpha chains?
These T cells recognize class II MHC and have an important role in activating B cells and other types of T cells
Helper T cell or CD4 T cell
These receptors recognize short linear stretches of amino acids
What are TCRs?
Along with MHC, these molecules on APCs stimulate Th cells.
What are the costimulatory molecules B7 and CD40
These 3 cell types are professional antigen presenting cells.
What are dendritic cells, macrophages, and B cells?
T cell equivalent of somatic mutation.
What is "there is no equivalent."
These T cells recognize class I MHC and have an important role in killing infected cells
CTL/ Killer T cell/ CD8 T cell
These receptors recognize conformational epitopes on proteins as well as carbohydrates.
What are BCRs?
These 2 phenomena are required for signaling by both BCR and TCR
What is clustering of receptors with bound antigen AND a costimulatory signal?
These APCs are antigen specific.
What are B cells?
These proteins, found on non-traditional T cells, are the counterparts to the BCR heavy and light chains
What are gamma and delta chains?
This type of T cell is most most abundant in intestine, uterus and tongue
Non-traditional T cell.
Recognition of this type of antigen by a TCR can lead to cell death
self peptides/antigens
These molecules strengthen the interaction between APC and T cells
What are adhesion molecules?
These APCs bridge the innate and adaptive immune systems
What are macrophages?
T cell equivalent to the bone marrow for B cells
What is the thymus?
This type of T cell is capable of recognizing lipid in context of CD1 MHC molecule
NKT cell
These molecules are found on most cells and present peptides from proteins produced from within the cell.
What are MHC class I molecules?
These cell types are required for activation of CTL (cytotoxic T cells)
What are dendritic (or antigen presenting) cells and Th cells?
These APCs migrate to the lymph nodes when activated.
What are dendritic cells?
T cell counterpart to Iga (alpha) and Igb (beta) (signaling component).
What is CD3?
This early stage T cell expresses both CD4 and CD8 co-receptors
What are Double-positive T cells?
These molecules present peptides from externally produced proteins and are only found on professional antigen presenting cells
What are class II MHC molecules?
This cytokine receptor is found on activated helper T cells. Binding of the cytokine signals the T cell to proliferate.
What is the IL-2 receptor?
This part of the innate immune system responds quickly to destroy invaders and signal other immune system players that an attack is on.
What is the complement system?