Endocrinology
Cardiology and HTN
Pulm/Crit
DM1+2
GI and Nephro
100

This should be your initial treatment in a patient with hyperprolactinemia and hypothyroidism.

What is correction of the hypothyroidism and retest serum prolactin levels.

100

This thiazide-like diuretic is recommended over HCTZ for patients with hypertension.

What is chlorthalidone?


(would also accept indapamide per up-to-date).

100

This condition is defined as airway dilation seen on imaging and is a risk factor for NTM and pseudomonas infection.

What is bronchiectasis?

100

This is how you calculate insulin dosing for a patient based on weight.

What is:

wt(lbs) x 0.25

wt(kg) x 0.55

with 40-50% basal and 50-60% bolus

100

These are the urine albumin-creatinine thresholds for albuminuria and risk of progression in CKD.

What is A1: <30, A2 30-300, A3 >300 mg/g

200

These are three possible causes of thyrotoxicosis in pregnant persons.

These are three possible causes of thyrotoxicosis in pregnant persons.

These are three possible causes of thyrotoxicosis in pregnant persons.

These are three possible causes of thyrotoxicosis in pregnant persons.

...

What are HCG-mediated hyperthyroidism, graves disease, and thyroiditis.

200

Patients with ESRD and hypertension should be treated based on this metric.

What is blood pressure on non-dialysis days.


Reduction in cardiac and vascular events only gained from controlled BP on non-dialysis days. Hold antihypertensive medications on HD days if patient has hypotension.

200

Development of this condition is an indication to stop montelukast therapy.

What is MDD or suicidality?

200

This is the eGFR cutoff for initiation of an SGLT2i in patients with T2D and CKD based on 2022 KDIGO guidelines.

What is eGFR >=20.


Note: once started, it is reasonable to continue even once eGFR falls below 20.

200

This "treatment" has the potential to reduce and even resolve fibrosis in MASLD/NAFLD patients.

What is weight loss?

300

Presence of any of these qualifiers with existing hypertension warrants evaluation for primary hyperaldosteronism in a patient with an adrenal mass.

What is:

sustained hypertension of >150/100 mm Hg on three separate measurements

resistant hypertension (uncontrolled hypertension on a three-drug regimen inclusive of a diuretic)

controlled blood pressure on four or more antihypertensives (one of which is a diuretic)

hypokalemia (either spontaneous or diuretic induced)

an incidentally discovered adrenal mass

a family history of early-onset hypertension or stroke at age <40 years

?

300

This is the correct treatment and duration of treatment for an LV thrombus complicating an acute MI.

What is anticoagulation for at least 3 months.
300

This "therapy" can slow the decline of FEV1 AND decrease mortality from COPD.

What is smoking cessation?

300

These are the two thresholds where SGLT2i start to lose glucose-lowering effects.

What are GFR <60 (attenuated) and GFR <30 (minimal).

300
This is the only test that can diagnose MASH as a cause of chronically elevated liver chemistries.

What is liver biopsy?


Note: Patients with elevated liver chemistries, a negative serologic evaluation for alternative causes, clinical features of the metabolic syndrome, and characteristic abdominal imaging are presumed to have MASLD 

400

This should be monitored regularly in FTM transgender patients on testosterone.

What is hemoglobin or hematocrit?
400

In patients with HFrEF and severe mitral valve regurgitation, this is the correct treatment.

What is GDMT?

400

This treatment shows improved QoL for patients with upper-lobe-predominant emphysema, FEV1 and DLCO of 20% of predicted or higher, and low exercise tolerance after completion of pulmonary rehab.

What is lung volume reduction therapy?

400

Per the American Geriatrics Society (and KPHI) guidelines, this is the A1c target for someone with complex or intermediate health.

(*DM complicated, 3+ comorbid, 2+ IADL impairment, mild-mod cog impairment)

What is a target A1c of 7.5-8.0% ?

400

With declining renal function, SGLT2i's lose the first effect but retain the second effect.

What are antihyperglycemic effects and cardiac benefits in CHF (reduced hospitalization and mortality, increased survival rate).


EMPA Kidney Trial

500

These are patients who should be started on a lower dose of levothyroxine for htyroid replacement.

What are patients >60 years of age and patients with CAD?


Note: start at 25 mcg/d

500

This trial showed that patients with symptomatic heart failure and EF <40% had reduced mortality and HF related hospitalizations on valsartan-sacubitril vs enalapril.

What is the PARADIGM-HF trial?

500

This is also known as the "futile crystalloid cycle" in patients with abdominal compartment syndrome.

What is a cycle of fluid administration to treat shock and overcome intraabdominal pressure, followed by third spacing and worsening of the shock?

500

This is one of the two most common autoantibodies in latent autoimmune diabetes in adults.

What is GAD65?

or

What is ICA?

500

The initial lab workup for MASLD/NAFLD to rule out other forms of liver disease.

What is hepatitis C antibody, hepatitis B panel, core and surface antigen, antimitochondrial antibody, alpha-1 antitrypsin, ceruloplasmin, and ferritin +/- transferrin saturation?


For bonus points: Anti-tissue transglutaminase antibody; Immunoglobulin G (IgG) level, antinuclear antibody, anti-smooth muscle antibody

Note: ANA and anti-smooth muscle are + in 20% of MASLD patients