How sweet it is to be wholehearted
Thiazide diuretics can result in which abnormality in lipid panel
Hypertriglyceridemia
Probe of choice to see deeper structures in abdomen
Curvilinear probe
Name two oral antidiabetic medications which has weight loss benefit
Metformin, SGLT2 inhibitor, GLP-1 agonist,
Test at bedside for determining stroke volume responsiveness to additional preload administration or 500 cc NS bolus
Passive leg raise test
Length of time for which ACE must be dced prior to initiation of Entresto
36 hours
FDA Approved medication class in addition to Diet and Maximally Tolerated Statin Therapy for Additional LDL-C Lowering and CVD benefit
Anti-PCSK9 Monoclonal Antibodies
What are the elements of Whipples` Triad of hypoglycemia?
1)Neuroglycopenic symptoms of hypoglycemia,
(2) Hypoglycemia
(3) relief of symptoms following ingestion of glucose.
Name three oral abx for treatment of Methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections (SSTIs)
Bactrim, doxycycline, clindamycin
Consistent with US Food and Drug Administration guidelines, metformin should not be used below this GFR
eGFR less than 30 mL/min/1.73m2,
Most common electrolyte abnormality seen in myxedema coma patients
Hyponatremia
80 Y M w DM, HFrEF, HTN, CAD p/f evaluation of pain in his perineum that is getting progressivelyworsening, he also noticed black color change on the skin around groin Vitals: BP 120/78, HR 45, RR 16, afebrile
Medications : Aspirin, coreg, dapaglifozin, entresto, metformin, chlorthalidone
Medication of culprit for his problem?
Dapaglifozin
COVID severe ARDS patients with
P/F<150
Fio2 >0.6
should be considered for this therapy and which trial showed the benefit
Prone ventilation, PROSEVA trial (2013 NEJM)
In this trial of patients with severe ARDS, prone positioning decreased 28-day all-cause mortality compared to supine positioning (16% vs. 32.8%)
What is the number of patients with severe ARDS would need to be treated with prone positioning (and not supine positioning) in order for one additional patient to not die within a 28-day period.
6
Risk of osmotic demyelination in the setting of overly rapid correction of chronic hyponatremia can be mitigated with these 2 interventions
DDAVP
Iv Hypotonic solution (Accept D5W )
Drug class which is recommended as the mainstay of treatment ( Class 1 ) in patients with clinical diagnosis of long QT syndrome and suggested in patients with silent QT syndrome
Beta blockers
Causative carcinogen in the most common primary pericardial tumour
ASBESTOS
Biochemical criteria for Iron Deficiency in Patients With Heart Failure
International guidelines on HF define ID as a serum ferritin <100 ng/mL or, when ferritin is 100-299 ng/mL, a transferrin saturation (TSAT) <20%.
Physician famous for his quotes :
Listen to your patient, he is telling you the diagnosis.
The good physician treats the disease; the great physician treats the patient
Sir WIlliam OSler
This anticonvulsant can cause metabolic acidosis without Fanconi syndrome through inhibition of carbonic anhydrase.
Board question !!
Topiramate
In addition to arrhythmias, dobutamine and milrinone may have this untoward side effect when initiated.
Hypotension
Cardiac myosin inhibition
In patients with GBS the 20-30-40 rule refers to these measurements
VC<20
NIF<30
MEP<40
According to new ACC/AHA 2022 HF guidelines recommendations for HFpEF
Class of medication with class 2A recommendation
Class of medications with class 2B recommendation
SGLT-2 inhibitors class 2A
ACEI, ARB,ARNI, BB, MRA weaker recommendation class 2B
This is the most common renal complication of sickle cell disease and is most often heralded by overt nocturia.
Urinary concentrating defect
RBC sickling and congestion in the vasa recta leads to ischemia and associated impairment of solute reabsorption by the ascending limb of the loop of Henle and impairs urinary concentrating ability.
BRASH syndrome is charactarized by combination of these 5 conditions