Stroke Basics
This occurs when a blood clot blocks the flow of blood to the brain.
What is an ischemic stroke?
This thrombolytic agent requires continuous infusion and has a shorter half-life.
What is alteplase?
This scale measures functional outcomes after a stroke, with a score of 0 indicating no symptoms and 6 indicating death.
What is the modified Rankin Scale (mRS)?
This is the primary reason tenecteplase can be administered more rapidly than alteplase.
What is its longer half-life and single bolus administration?
This type of medication is commonly used to dissolve blood clots in patients with ischemic stroke.
What are thrombolytics?
This drug can be administered as a single bolus and has a longer half-life than alteplase.
What is tenecteplase?
Both tenecteplase and alteplase were shown to be effective, but this treatment had better safety outcomes.
What is tenecteplase?
In the studies, tenecteplase was found to be noninferior to alteplase in this primary outcome.
What is restoring perfusion?
What is tPA?
Tenecteplase has higher specificity for this protein, which helps break down blood clots.
What is fibrin?
Tenecteplase improved stroke symptoms more than alteplase. What was this improvement measured by?
What is the NIH Stroke Scale?
Both tenecteplase and alteplase had this percentage of patients with symptomatic intracerebral hemorrhage.
What is 1%?