Stem Cells
A cell with the unique ability to develop into specialised cell types in the body.
What is a stem cell?
Glands on which this article is based on
What are adrenal glands?
Origin of somatic cells used to produce hiSCs
Urine, Skin and Blood
Embryonic stem cells, Adult stem cells and Induced Pluripotent stem cells
What are the different types of stem cells?
The location where ACTH is released from
What is anterior pituitary gland?
Definition of a congenital disease
What is a disease that is occurring from birth due to faulty genes?
The characteristic of a stem cell to differentiate into specialized cells
What is pluripotency?
An acronym for ACTH
What is adrenocorticotropic hormone?
The two primary cell donors
Healthy donors and patients with congenital adrenal disorders
Reprogramming
What is the process of producing induced pluripotent stem cells by adding transcription factors to somatic stem cells?
Two of the many hormones released by adrenal cortex
Testosterone, Estrogen, Cortisol, Aldosterone
This was a test for the hiSCs (if it was a success or not)
In vivo implantation experiment in mice
The three uses of induced pluripotent stem cells
1) Model diseases
2) Drug testing for disorders
3) Provide patient-specific cell therapy
The three categories of steroids produced by the adrenal cortex
What are mineralocorticoids, glucocorticoids and androgens?
An acronym for hiSCs
What is human inducible steroidogenic cells?