Show:
Lab Values
The PRESSURE is on!
Heart, don't fail me now!
To be honest, you're a CLOT!
Side effect smorgasbord!
100

What is the normal lab value for aPTT?

What is the therapeutic lab value for aPTT?

40 seconds

60-80 seconds (1.5-2x the baseline)

100

1% of patients lose consciousness when they take the first dose of this blood pressure med.

Bonus: What category does it belong to?

What is prazosin? 

Adernergic antagonist

100
When transitioning a patient from an ACE to an ARNI, how long should we wait, and why?

36 hours because of the risk of angioedema

100

Drug of choice for DVT.

Enoxaprin (Low molecular weight heparin)

100

If a patient has received heparin and their platelet count comes back as <100,000 then they have most likely developed this SE.

Bonus: What does that mean for the patient?

HIT (heparin induced thrombocytopenia)

They should never be on heparin again because their body has developed antibodies.

200

What is the normal lab value for PT?

What is the therapeutic lab falue for PT?

12 seconds

12-24 seconds (1-2x the baseline)

200

This class of drug blocks the conversion of angiotensin 1 to angiotensin 2, leading to vasodilation and decreased fluid volume.

What is it's prototype?

What are ACE Inhibitors?

lisonopril

200

A provider prescribes Carvedilol for a patient with heart failure, and a new diagnosis of COPD. What is the concern?

carvedilol is beta non selective and so can cause bronchoconstriction, and shouldn't be used in patients with pulmonary issues. 
200

Heparin can be given by these two routes?

Sub Q and IV

200

Which drugs on this exam have a SE of orthostatic hypotension?

  • Nitroglycerin 

  • CCB’s 

  • Direct Vasodilator’s (hydralazine, isosorbidedinitrate) 

  • RAAS drugs 

  • Alpha/Beta Blockers (Caredilol)  

  • BB 

  • Prazosin  (alpha antagonist) 

  • Lasix (furosemide) 

300

What is the therapeutic level for an INR (internalized ratio?

Is INR or PT a more accurate lab value?

2.0- 3.0

INR

300

This class of drug blocks receptors for angiontensin 2 after it is formed and is a potent vasodilator. 

What is it's prototype?

What are ARB's?

Valsartan

300

What lab value increases the risk of digoxin toxicity?

Low potassium

300

The antidote for this drug is idarucizumab. 

Dabigatran
300

Which drugs on this exam have a SE of reflex tachycardia?

  • Hydralazine (RT) 

  • Prazosin (RT) 

  • Nifedipine (RT) 

  • Diltiazem (RT) 

  • Isosorbide dinatrate 

400

What is the therapeutic range for digoxin?

0.5 - 0.8ng/ml

400

Which hypertension medications work directly on the heart?

Cardio selective beta blockers (metropolol), Alpha/Beta blockers (carvedilol), Non-Dihydropyridine CCB's (verapamil and diltiazem)

400

What is the typical heart failure recipe?

ACE or ARB or ARNi

BB

Diuretic (HCTZ or furosemide)

400

This class of drug is most effective for preventing arterial thrombi.

Anti platelet agents

400

What is the SE of clonidine if it is stopped cold turkey?

Rebound hypertension

500

What is the most accurate lab value for Heparin, and what are it's therapeutic levels?

Anti-factor Xa 

0.3-0.7 IU/ml

500

What are the 3 categories of diuretics, their prototypes, and where do they work in the kidneys?

Loop (furosemide) - Loop of Henle

Thiazide (hydrochlorothiazice) - Distal tubule

K Sparing (spironolactone) - Distal tubule

500

What is the concern if a patient on nitroglycerin is also taking sildenafil, tadafil or vardenafil? 

Life threatening hypotension and cardiovascular collapse! 

500

What is the time frame for administering alteplase (tPa) for someone who has had an MI?

A CVA?

MI: 6 hours


CVA: 3 hours

500

Which drug has a SE of lupus like symptoms?

hydralazine