Trans-formation
Transformation
What is the overall charge of DNA and why?
The phosphate groups give DNA a negative charge.
What three elements are nucleotides made up of?
Phosphate
Deoxyribose sugar
Nitrogenous base
Who discovered Nuclein?
Friedrich Mischer
When mice were injected with R strand, what happened?
no infection
alternating sugar and phosphate groups.
how are nucleotides linked?
phosphodiester bonds
Where was Nuclein found?
in the nucleus of cells
What agent is responsible for the transforming process?
DNA
What is DNA's structure?
right handed double stranded helix
What nitrogenous bases are purines?
Adenine and Guanine
Miescher's work identified the presence of this element in nuclein, which was a major clue that the substance was not a protein.
phosphorus
What bond holds the nitrogenous bases together in DNA?
Hydrogen Bonds
What does Cytosine (C) bond with in DNA?
Guanine
What is nuclein now known as
DNA
can R strand DNA transform R to S?
no
what directions do the helices run?
antiparallel
What did Erwin Chargoff's experiment reveal?
nucleotides are arranged so that there are equal amounts of A & T, and C & G
why did Miescher name this substance nuclein?
Because it was discovered in the nucleus of cells.