Pituitary
1st line therapy for symptomatic prolactinoma
What is Cabergoline?
Target A1c to obtain prior to elective surgery
8
Decreases sugar production by the liver.
Biguanides (Metformin)
New unilateral gynecomastia should raise suspicion for ______
Breast Cancer
The capital of Nevada
What is Carson City?
Name tests for Cushing syndrome d/t hyperfunctioning pituitary adenoma
Midnight salivary cortisol, 24-hr urine free cortisol, dexamethasone suppression test
Treatment for nephrogenic DI (2 parts)
Low-solute diet, thiazide diuretic
Solute drives fluid losses, diuretic induces mild volume contraction >> proximal solute & water resorption
Adjuvant treatment for thyroid storm that blocks release of T4 and T3
Iodine
Name 4 causes of secondary hypogonadism
Prolactinoma, meds (opioids), alcoholism, obesity, hemochromatosis, liver/kidney disease, untreated OSA
Name of the trial that set the blood sugar goal for patient's hospitalized in the ICU
What is NICESUGAR?
In hypopituitarism, thyroid hormone replacement should only be done after ______
Adrenal insufficiency is evaluated & treated
Which antibody is most specifically associated with type I diabetes?
Antibodies to glutamic acid decarboxylase (GAD-65)
Syndrome of vitiligo, autoimmune thyroid and adrenal disease , type 1 DM, and hypopituitarism
Polyglandular autoimmune syndrome
Additional evaluation for someone in myxedema coma and most likely in which season
Assess for adrenal insufficiency
Winter
Born this day (3/27/1962) in Knoxville, TN, this cinematographer would go on to direct hits such as Pulp Fiction, Resivoir Dogs, and many others
Who is Quentin Tarantino?
Indications for surgery in non-prolactin pituitary adenomas
1. If hypersecreting GH, ACTH, or TSH
2. Large, nonfunctioning tumors if growing or affecting vision
Name of trial that showed basal bolus was more effective than sliding scale for inpatients
bonus if you know the clinical site
What is Rabbit 2
Which medication that increases insulin release is contraindicated with pregnancy?
Sulfonylureas (Glipizide)
Cause of chronic hypovolemic hyponatremia and hyperkalemia with hyperpigmentation
Primary adrenal insufficiency (Addison disease)
The 2024 NCAA Men's Basketball Champions
Who are the UConn Huskies?
Patients with evidence of DI and a thickened pituitary stalk on MRI should be evaluated for ______
Infiltrative diseases (sarcoidosis, Langerhans cell histiocytosis)
Which medication has increased risk of bladder cancer?
Thiazolidinediones
Name 3 medications that decrease absorption of levothyroxine?
Antacids
Cholestyramine
Iron supplements
Orlistat
Sucralfate
Sevelamer
Proton pump inhibitors (PPIs)
Rifampin
Eponymous phenomena occurring when excess iodine intake acutely inhibits thyroid hormone synthesis
What is the Wolff-Chaikoff effect
For the third time since no one has gotten it right yet:
The name of Dr. Schwade's cats
Who are Rosie and Daisy?