Lines of Defense
Which line of defense includes memory cells (like B & T cells)
What is...
The 3rd line of defense - adaptive immunity
What part of the body is responsible for making the progenitors of B & T cells?
What is...
The Bone Marrow
What is the scientific reason for a fever?
What is...
removal of iron in blood to slow down bacterial replication
What are the two types of T cells?
What are...
T helper & T killer (cytotoxic) cells
What type of immune disease is Lupus?
What is...
An Auto-immune disease
What is...
Inflammation
What part of the immune system is where memory cells are stored for later us?
What are...
The lymph nodes
What cells in the innate immune system target mostly viruses & cancer cells?
What are...
Natural Killer (NK) cells
What do B cells secrete, that "handcuff" foreign antigen?
Antibodies
Immunocompromised
Which line of defense includes your skin & your mucous membranes?
What is...
the FIRST line of defense
Where do T cells mature?
What is...
the Thymus
What cells in the innate immune system are the most prevalent, but the least longevity?
What are...
Neutrophils
Which branch of the adaptive immune response relies on MHC complexes & antigen presentation from cells in danger?
The cell-mediated response
In an ELISA, when you have an antigen first, then you add 2 antibodies...what type of ELISA did you just use to diagnose your patient?
An indirect ELISA
Macrophages (big eaters) and the complement system are examples of what line of defense?
What is...
Innate Immunity (the second line of defense)
What are...
the saliva, sweat, tears & mucous membranes
What part of the innate immune system forms "MACs" or membrane-attack complexes, to cause apoptosis?
What is...
the complement system
What part of the antibody is specific to the antigen it is searching for?
The antigen-binding site OR the variable region
Antibodies have 4 "chains", in 2 categories, name these categories & the bonds that hold them together.
What are...
Heavy Chains & Light Chains held together by disulfide bridges
This line of defense has 2 branches, the humoral & the cell-mediated.
What is...
Adaptive Immunity (the 3rd line of defense)
What parts of the immune system are long chains of amino acids that can poke holes in invaders to destroy them, without mounting memory?
What is...
the complement system
What cells in the innate immune system are BIG EATERS & engulf large amounts of foreign material once recruited?
Macrophages
What do we call B cells that are activated & secreting antibody?
Plasma Cells
Which type of immune cell is also called a CD4 cell, due to a specific CD4 proteins that is on its surface after maturation?
What is...
A T-helper Cell