Crack the Pancreas
Zenpep contains these three pancreatic enzymes.
What are lipase, protease, and amylase?
An avocado is an example of this macronutrient.
Fat (lipid)
The gold standard of PERT dosing is this principle.
What is weight-based dosing?
An HCP might say this as the biggest reason why they prefer one PERT over the other.
What is "insurance coverage" or "coverage"
What are Zenpep's contraindications?
What is NONE!
What percentage of the pancreas is exocrine tissue?
What is 85%?
Lipase helps digest this.
What are lipids (fats).
The enteric coating allows release at this area of the GI tract.
What is the small intestine?
This HCP often provides guidance regarding nutrition and enzyme management.
What is the maximum dosage per kilogram (kg) of lipase units?
What is 2,500?
The ductal cells in the pancreas have this function.
Secrete bicarbonate and lower the pH of food.
A patient eating a meal twice as large as usual may require consideration of this dosing adjustment.
What is increasing enzyme dosage based on meal fat content?
Approximately 85% of people with CF experience this condition.
What is EPI?
As of August 2026, how many more individuals are covered by Zenpep over Creon?
What is 10 million
What would you say if an HCP asks if they can use Zenpep for a patient who is on an enteral feed (aka "tube feed")?
What is a MIRF/talk to Alla/ only stay on label conversations
CF patients are likely to develop EPI because of this reason.
The fluid that is in their lungs leaks out and clogs the pancreatic ducts that secrete enzymes.
This vitamin group is commonly deficient in patients with EPI.
What are fat-soluble vitamins?
What percentage of lipid absorption do pancreatic enzymes account for?
What is 90%?
What is the maximum annual savings limit for L2T?
What is $10,000
What does CFA stand for?
What is Coefficient of Fat Absorption?
The acinar cells in the pancreas have this function.
Secrete digestive enzymes
At which pH is the Zenpep capsule designed to release the enzymes?
What is 5.5 or greater?
This dosage component is most commonly used when calculating PERT dosing.
What are lipase units?
What is the maximum annual savings limit for Z-Save?
What is $6,500?
______ is a rare serious adverse reaction initially described in association with use of high-dose pancreatic enzyme products
Fibrosing colonopathy