Anatomy of the Urinary System
Physiology & Function
EEOICPA & Covered Conditions (Urinary System)
Consequential Illnesses (Urinary System Under EEOICPA)
EEOICPA Procedures & Claim Development
100
This bean-shaped organ filters blood and produces urine.
What are the kidneys?
100
This process describes the kidneys’ removal of toxins, drugs, and waste from the bloodstream.
What is filtration?
100
This kidney disease is often recognized as a covered condition for uranium millers and miners under RECA and EEOICPA due to heavy-metal exposure.
What is chronic kidney disease (CKD)?
100
This cardiac-related condition is commonly accepted as consequential to chronic kidney disease because reduced renal function increases vascular resistance.
What is hypertension?
100
This type of claim is filed when a new medical condition occurs because of an already-accepted condition.
What is a consequential illness claim?
200
These tiny structures inside the kidney perform filtration and are the functional unit of the renal system.
What are nephrons?
200
The condition in which the kidneys suddenly lose function over hours or days.
What is acute kidney injury (AKI)?
200
This condition, defined by protein in the urine, is often used as early evidence of renal injury in exposure-based claims.
What is proteinuria?
200
This type of anemia can occur when damaged kidneys stop producing adequate erythropoietin.
What is anemia of chronic disease (or anemia of CKD)?
200
This primary or secondary urinary cancer is accepted under the SEC if SEC WH requirements are satisfied.
What is renal cancer?
300
This muscular sac stores urine until it is expelled.
What is the bladder?
300
The part of the nephron responsible for most nutrient and electrolyte reabsorption.
What is the proximal tubule? 
300
Under EEOICPA guidance, a kidney condition may be accepted if exposure is shown to have caused, contributed to, or this term—meaning worsened a pre-existing illness.
What is aggravated?
300
This swelling of the legs and feet can develop from reduced kidney function leading to sodium and fluid retention.
What is peripheral edema?
300
This urinary system cancer is approved under the SEC if SEC WH requirements are met AND the diagnosis occurred at least five years after the initial exposure.
What is bladder cancer?
400
The tube that carries urine from the kidney to the bladder.
What is the ureter?
400
This rate, estimated using serum creatinine, is used to stage chronic kidney disease.
What is eGFR (estimated glomerular filtration rate)?
400
This chronic condition characterized by cyst formation and progressive renal enlargement is not typically caused by toxic exposures but may qualify if exposure aggravated progression.
What is polycystic kidney disease (PKD)?
400
Damage to the kidneys may impair vitamin D activation, contributing to this bone-weakening condition.
What is osteoporosis?
400
Claims examiners often request this type of report from to quantify the intensity, duration, and significance of exposure.
What is an industrial hygiene report?
500
This hormone, produced by the kidneys, regulates red blood cell production.
What is erythropoietin?
500
The kidneys regulate this electrolyte, which is critical for heart rhythm and nerve conduction.
What is potassium?
500
These urinary system cancers are covered under the SEC.
What are renal and bladder cancer?
500
Reduced kidney function can worsen this endocrine condition because insulin clearance slows and glucose metabolism changes.
What is secondary worsening of diabetes control?
500
This DEEOIC unit is responsible for issuing the final decision after the District Office issues a recommended decision.
What is the Final Adjudication Branch (FAB)?