The Science Behind LyGenesis
Diseases & Unmet Needs
The Pipeline & Clinical Trials
100

This part of the body is used as a bioreactor to grow functional ectopic organs.

  • What are lymph nodes?

100

LyGenesis is developing cell therapies to treat this end-stage organ disease, which affects millions worldwide.

  • What is end-stage liver disease (ESLD)?

100

LyGenesis’s liver therapy is currently in this phase of clinical trials.

What is Phase 2A?
200

LyGenesis’s approach reduces reliance on this traditional, high-risk medical procedure.

What is Organ Transplantation?
200

In addition to the liver, LyGenesis is working on regenerating this gland, which plays a crucial role in immune function.

What is the thymus?

200

Before moving to human trials, LyGenesis tests its therapies in these two types of animal models.

  • What are small and large animals?

300

The outpatient procedure used to engraft liver cells into lymph nodes is called this.

  • What is an endoscopic ultrasound?

300

The LyGenesis pipeline includes a therapy aimed at treating this autoimmune condition that affects insulin production.

  • What is Type 1 diabetes?

300

A therapy must pass these five stages before getting FDA approval.

  • What are discovery, small animal testing, large animal testing, Phase 1, Phase 2, and Phase 3?

400

LyGenesis's cell therapy technology is considered allogeneic because it uses this type of donor material.

  • What are donor-derived cells?

400

LyGenesis’s therapy for end-stage renal disease targets this pair of vital organs.

What are Kidneys?

400

This U.S. regulatory agency oversees the approval of new medical treatments like those developed by LyGenesis.

  • What is the FDA (Food and Drug Administration)?