EPS
Substance Abuse
Mood Stabilizers
Antipsychotics
General Medicine
100
This form of EPS is described as somatic restlessness and the inability to stay still or calm.
What is akathisia?
100
This class of medication are given to prevent delirium tremens in patients detoxing from alcohol.
What is benzodiazepines (or benzos)?
100
Mood stabilizers require drug level monitoring, which are typically drawn at this time.
What is before the dose?
100
Many antipsychotics have anticholinergic properties that cause these symptoms.
What are dry mouth, constipation, blurred vision and urinary hesitancy?
100
Clonidine is a commonly used PRN medication for blood pressures above 160/100 and should only be held during these parameters
What is HR<55 or SBP<110?
200
This form of EPS occurs after at least 6 months of antipsychotic use and may not resolve with discontinuation of the drug
What is tardive dyskinesia?
200
This antidepressant is also FDA-approved for smoking cessation.
What is Zyban/Wellbutrin (buproprion)?
200
Therapeutic levels of this mood stabilizer are between 75 and 125 mcg/mL, which allow it to be just as effective as lithium in patients with Bipolar Disorder.
What is Depakote (valproic acid)?
200
Some antipsychotics cause this BP lowering phenomenon, which is a common reason for falls.
What is orthostatic hypotension?
200
This drug to treat high TSH should be given on an empty stomach.
What is Synthroid (levothyroxine)?
300
This form of EPS is defined by bradykinesia, rigidity, tremor or akinesthia and is usually responsive to anticholinergic medications.
What is parkinsonism?
300
These two medications are given to patients addicted to opioids to help reduce withdrawal and prevent cravings.
What is methadone and Suboxone?
300
It is important to stay well hydrated with this mood stabilizer to avoid toxicity.
What is lithium?
300
This serious cardiac side effect can occur with antipsychotics that could potential lead to fatal arrhythmias such as Torsades de Pointes
What is QT prolongation?
300
Common symptoms of this electrolyte deficiency include headache, lethargy and obtundation, which can be due to drug-induced SIADH.
What is hyponatremia?
400
This antipsychotic has the least risk for causing EPS.
What is Clozaril (clozapine)?
400
Campral (acamprosate) is used to prevent the use of this substance.
What is alcohol?
400
Symptoms of this mood stabilizer’s toxicity include lethargy, coarse tremor, confusion, seizures, and coma and may even result in death.
What is lithium?
400
This long-acting, injectable antipsychotic requires loading doses (234 mg IM on day one, then 156 mg IM one week later).
What is Invega Sustenna?
400
A common sign of toxicity when levels of this antiepileptic drug get too high (>20) is nystagmus.
What is Dilantin (phenytoin)?
500
This medication can be prescribed to prevent EPS in patients receiving antipsychotics?
What is Cogentin (benztropine)?
500
These commonly prescribed pain medications are not detected by urine drug screens.
What are oxycodone, hydromorphone and hydrocodone?
500
Serious rashes (i.e. Stevens-Johnson syndrome) can occur with this mood stabilizer, which typically present during the initial 2-8 weeks of therapy.
What is Lamictal (lamotrigine)?
500
This second generation antipsychotic requires regular CBC monitoring due to the rare, but serious side effect of agranulocytosis.
What is Clozaril (clozapine)?
500
Thiamine is given to alcoholics in order to prevent this disease state.
What is Wernicke’s encephalopathy?