Antibiotics
Write one cephalosporin from each generation on the board
1st- cefalexin, cefazolin
2nd- cefuroxime, cephamycin (cefoxitin, cefotetan)
3rd- ceftriaxone, cefotaxime, cefpodoxamine, ceftazadime
4rd- cefepime
5th- ceftaroline
What are the active forms of Prednisone and Cortisone?
Prednisolone and Cortisol
What would you give for a patient with progressive dyspnea and cough, that present with an FEV1 of 70%, gets out of breath getting dressed (mMRC >2, CAT >10), and has had 0 exacerbations?
LABA + LAMA
What percent of adults pretend not to be home on Halloween?
21% or 1 in 5
What is the gold standard for MRSA coverage?
Vanco
What drug is used for both the treatment of allergic rhinitis in children as well as asthma?
Montelukast (Singulair)- Leukotriene Receptor Antagonist
What is a side effect of pyrazinamide?
Hyperuricemia
What's the most common injury related to Halloween?
-55% Pumpkin carving
-25% are due to falls while decorating/trick-or treating
- 20% miscellaneous (lacerations, ingestions, rashes getting hit by a car)
A 45-year-old patient presents with severe intra-abdominal infection after surgery. Culture results are pending, but empiric therapy with a broad-spectrum beta-lactamase inhibitor is initiated to cover anaerobes and Gram-negatives, including Pseudomonas. Which antibiotic regimen would be most appropriate for the empiric therapy?
zosyn
A 28-year-old woman presents with year-round nasal congestion, sneezing, and postnasal drip. She has tried antihistamines, but the relief is minimal. She has been prescribed a nasal steroid (Nasacort) one week ago but returns back to the clinic complaining of no relief. Why is she not experiencing any relief?
Nasal steroids do not have immediate effect, peak response will not be observed for 2-3 weeks.
A 35-year-old healthcare worker tests positive on a routine tuberculin skin test (TST) with an induration of 12 mm. Patient has no symptoms of active tuberculosis, and chest X-ray is normal. Patient has no known drug allergies and has never been treated for TB before. What is the most appropriate treatment regimen for their TB infection to prevent progression to active disease?
3 months INH plus Rifampin/Rifapentine given once weekly
(latent TB)
What state produces twice more pumpkins than any other?
Illinois
A patient with a history of anaphylaxis to penicillin needs treatment for a Gram-negative urinary tract infection. What antibiotic can be safely used given the absence of cross-reactivity with penicillins, but which shares a side chain with ceftazidime?
A 55-year-old man with rheumatoid arthritis has been on long-term prednisone therapy. He abruptly stops taking his medication. Shortly afterward, he experiences fatigue, dizziness, nausea, hypotension, and salt cravings. Lab results reveal hyponatremia, hyperkalemia, and low cortisol levels. What condition is he likely experiencing?
Secondary adrenal insufficiency caused by HPA axis suppression, leading to Addison-like symptoms due to a lack of cortisol production after stopping steroids without proper tapering
What monoclonal antibody therapy targets interleukin-5 (IL-5) or its receptor, making it an add-on option for patients with severe eosinophilic asthma uncontrolled on high-dose ICS-LABA therapy?
Mepolizumab or Benralizumab
What are the origins of Halloween? What did it used to be celebrated as/ by whom?
The Celts celebrated Samhain on October 31 to mark the end of the harvest and the beginning of winter. They believed that the boundary between the living and the dead was blurred on this night, and that the ghosts of the dead returned to earth Celtic Festival of Samhain