Signs and symproms
Complications
Graves' disease specific
Common amongst all hyperthyroidisms
100

An unintended symptom due to an increase in calorie burning for basic bodily functions

What is unintended weight loss?

100

What are 3 cardiovascular complications?

Tachycardia, Palpitations, Atrial fibrillation, High-output heart failure, Worsening angina, Increased risk of stroke

100

This eye sign occurs in Graves’ disease because autoimmune antibodies trigger inflammation and swelling behind the eyes, pushing the eyeballs forward.

What is exophthalmos?

100

Both Graves’ disease and other causes of hyperthyroidism can produce this enlargement of the thyroid gland, although the pattern may differ.

What is a goitre?

200

A symptom caused by increased sympathetic activity of the gut.

What is diarrhea?

200

What are 3 eye complications? Specifically related to Grave’s disease

Dry, redness, Bulging eyes, Double vision, Light sensitivity, Eye pain, vision loss

200

Unlike toxic multinodular goitre or thyroiditis, Graves’ disease causes this skin change because immune cells stimulate connective tissue and glycosaminoglycan buildup in the lower legs.

What is pretibial myxoedema?

200

Both Graves’ disease and other forms of hyperthyroidism commonly show increased levels of these thyroid hormones due to excessive thyroid activity.

What are T3 and T4?

300

A symptom caused by excess heat generated from increased metabolism?

What is heat intolerance/sweating?

300

What are 3 metabolic complications?

Weight loss, Muscle weakness, Fatigue, Heat intolerance, Tremor, Increased sweating, Diarrhoea, Poor sleep and anxiety symptoms

300

These antibodies are positive in Graves’ disease because the disorder is autoimmune and the antibodies mimic TSH, continuously stimulating the thyroid gland.

What are TSH receptor antibidies (TRAb)?

300

This pituitary hormone is usually decreased in Graves’ disease, toxic multinodular goitre, and toxic adenoma because high thyroid hormone levels suppress it through negative feedback.

What is TSH?

400

An observable sign caused by thyroid cell overstimulation.

What is an enlarged thyroid gland/goitre?

400

What are 2 bone complications?

Reduced bone mineral density, Osteopenia, Osteoporosis, Increased fracture risk

400

This scan finding occurs in Graves’ disease because the entire thyroid gland is overstimulated by circulating antibodies, causing all parts of the gland to actively take up iodine.

What is diffuse radioactive iodine uptake?

400

Because excess thyroid hormone increases sympathetic nervous system activity, these symptoms are commonly seen in hyperthyroid disorders. 

What are neuropsychiatric symptoms of hyperthyroidism? (anxiety, irritability, nervousness)

500

A symptom caused by increased sympathetic activity of the gut.

What is palpitation?

500

What are 2 pregnancy complications?

Miscarriage, Preterm birth, Low birth weight, Pre-clampsia, Maternal heart failure, Fetal or neonatal thyroid dysfunction

500

Graves’ disease is more associated with conditions like Type 1 Diabetes and Rheumatoid Arthritis because Graves’ itself is this type of disorder.

What is an autoimmune disease?

500

Rapid heart rate, tremor, sweating, and heat intolerance occur in Graves’ disease and other hyperthyroid disorders because of this kind of symptom.

What are hypermetabolic symptoms?