Signs & Symptoms
Maeve has experienced this bowel symptom intermittently alongside abdominal discomfort and bloating.
What is diarrhoea?
Chronic iron malabsorption in untreated coeliac disease can eventually produce this common haematological complication.
What is iron-deficiency anemia?
Which nutrient deficiency is particularly common in untreated coeliac disease?
What is iron?
What substances can become deficient in a patient with Coeliac Disease?
What is iron deficiency (anaemia), vitamin B12, folate deficiency, vitamin d deficiency (osteoporosis)?
A patient with coeliac disease develops osteopenia. Malabsorption of which two nutrients is most directly responsible for the increased risk of poor bone mineralisation?
What is Vitamin D and Calcium?
Malabsorption of nutrients followed by bacterial fermentation can explain these two prominent abdominal symptoms experienced by Maeve.
What are bloating and excessive flatulence?
Reduced calcium and vitamin D absorption can lead to loss of bone mineral density and this skeletal complication.
What is osteopenia/osteoporosis?
A person with long-term untreated coeliac disease and resultant vitamin D deficiency might experience what disease?
What is osteoporosis or osteomalacia?
Coeliac disease raises the risk of developing what three cancers?
What is small bowel cancer, small bowel lymphoma and Hodgkin lymphoma?
Fat malabsorption can cause stools that are pale, bulky, greasy, and difficult to flush; this is called this.
What is steatorrhoea?
Maeve has chronic fatigue and low iron despite having no obvious history of blood loss. In coeliac disease, damage to this region of the small intestine particularly explains her iron deficiency.
What is the duodenum/proximal small intestine?
Maeve develops persistent focal foot pain after several days of hiking despite no acute trauma. If coeliac disease has impaired her bone health, this complication should be considered.
What is a stress fracture?
Which group of nutrients may be poorly absorbed due to coeliac-related malabsorption?
What is fat-soluble vitamins (A, D, E and K)?
What other inflammatory conditions are associated with Coeliac Disease?
What is lactose intolerance, IBD (Crohn’s Disease and UC)?
A patient has coeliac disease and develops easy bruising. Which nutrient deficiency could explain this, and why?
What is Vitamin K?
This characteristic intensely itchy skin condition, usually affecting extensor surfaces, is an important extra-intestinal manifestation of coeliac disease.
What is dermatitis herpetiformis?
This rare intestinal lymphoid malignancy has a recognised association with longstanding untreated or refractory coeliac disease.
What is enteropathy-associated T-cell lymphoma (EATL)?
Why can coeliac disease lead to nutrient deficiencies?
Damage to the small-intestinal mucosa reduces nutrient absorption
Malnutrition is a consequence of untreated Coeliac disease. Name 2 further consequences of malnutrition.
Inability to recover from recover from wounds and infections, fatigue, dizziness and confusion, (children) stunted growth and delayed development
A patient with untreated coeliac disease develops night blindness. Which deficiency should be suspected?
What is Vitamin A? Needed to see in low light.
What causes the excessive flatulence?
What is the bacterial fermentation of unabsorbed nutrients producing excess intestinal gas?