Pasakalye sa sentrong ugat
Which of the following when added to levodopa exert a potentiating effect?
A. Amantadine
B. MAOI
C. Carbidopa
D. Dopamine Agonist
d. Reuptake transporters
C. Carbidopa
What is the primary mechanism of action of SSRIs (Selective Serotonin Reuptake Inhibitors)?
A. Blocking dopamine receptors
B. Inhibiting serotonin reuptake
C. Enhancing GABAergic activity
D. Inhibiting acetylcholine breakdown
B. Inhibiting serotonin reuptake
What precaution is recommended for patients receiving clozapine?
A. Monthly blood counts for one year
B. Quarterly blood counts
C. No blood count monitoring is necessary
D. Weekly blood counts for the first 6 months, then every 3 weeks
D. Weekly blood counts for the first 6 months, then every 3 weeks
This drugs elimination rate can be increased significantly by alkalinization of the urine
A. Mepobamate
B. Midalozam
C. Zalepon
D. Phenobarbital
D. Phenobarbital
Which of the following reduces the degradation of dopamine?
A. Benzotropine
B. Levodopa
C. Galantamine
D. Amantidine
C. Galantamine
Which enzyme is irreversibly inhibited by MAOIs (Monoamine Oxidase Inhibitors) like phenelzine?
A. MAO-A
B. MAO-B
C. Both
D. COMT
C. Both
Which ocular complication is associated with Chlorpromazine use?
A. Corneal deposits
B. Lenticular deposits
C. BOTH
D. NEITHER
C. BOTH
A patient on medication of anxiety-related insomnia complains of persistent somnolence and lassitude in the mornings. Of the following, the most likely medication given is:
A. Trialozam
B. Zolpidem
C. Oxazepam
D. Diazepam
D. Diazepam
The following is a contraindication for the use of dopamine agonists
A. DMT2
B. Epilepsy
C. Active Peptic ulceration
D. Hypertension
C. Active Peptic ulceration
Which antidepressant is known for causing the least sexual dysfunction?
A. Paroxetine
B. Sertraline
C. Bupropion
D. Fluoxetine
C. Bupropion
Amphetamines can aggravate schizophrenia or produce psychosis because it is a dopamine _____:
A. Receptor agonist
B. Precursor
C. Releaser
D. Reuptake inhibitor
C. Releaser
A person experiences sleep difficulties which does not significantly resolve with nonpharmacologic strategies. He denies feelings of anxiety. Which of the following is the BEST treatment option?
A. Zaleplon
B. Thiopental
C. Triazolam
D. Clonazepam
A. Zaleplon
A patient newly diagnosed with schizophrenia was prescribed an appropriate medication. After 8 days of medication, he was noted to be dragging his legs with his neck turned on his side, his fingers curled inside and he had difficulty in talking. He was brought to the ER and was diagnosed with dystonia. Which of the following may have been affected in this condition
A. Locus ceruleus
B. Substantia nigra
C. VTA
D. Nucleus accumbens
B. Substantia nigra
A 27-year old postgraduate student is taking venlafaxine at low doses. Which of the following effects is expected to be predominant?
A. Serotonergic
B. Dopaminergic
C. Antimuscarinic
D. Noradrenergic
A. Serotonergic
Which cardiac malformation is associated with lithium salts use during pregnancy?
A. Tetralogy of fallot
B. Ebstein anomaly
C. TOGA
D. Ventricular septal defect
B. Ebstein anomaly
A patient is prescribed with alprazolam for the first time for generalized anxiety disorder. He is counselled to avoid alcohol at all times. The main reason for this is:
A. additive sedative effects
B. precipitate disulfiram reaction
C. reduce hypnotic effect of alprazolam
D. facilitate GIT absorption of the drug
A. additive sedative effects
DONEPEZIL
A. Synthesis
B. Metabolism
C. Degradation
D. Release
C. Degradation
A 45-year old woman taking an antidepressant organized a cheese party. After 4 hours, she was brought to the ER due to hypertensive crisis. What antidepressant is she taking?
A. Citalopram
B. Duloxetine
C. Trimipramine
D. Phenelzine
D. Phenelzine
A 28-yr-old woman was diagnosed with schizophrenia. She was brought to ER due to high-grade fever, increased agitation, and confusion. At the ER, labile blood pressure with profuse diaphoresis, sialorrhea, and muscle rigidity was noted. Which of the ff is manifested by the patient?
A. Parkinsonism
B. Tardive dyskinesia
C. Neuroleptic malignant syndrome
D. Agranulocytosis
C. Neuroleptic malignant syndrome
A patient who has been taking a new hypnotic agent suddenly discontinues the medication after 2 weeks and is now complaining of a return of his insomnia. Of the following, the MOST likely drug taken is:
A. alprazolam
B. eszopiclone
C. thiopental
D. tasimelteon
B. eszopiclone