Soft Tissue Tumors
Bone Tumor Basics
Location is Everything
Diagnostic Imaging Clues
100

This sub-type of malignant melanoma often appears on palmer, plantar, and subungal surfaces.

What is acral letiginous melanoma?

100

This primary malignant bone tumor is characterized by the production of osteoid, an immature form of bone matrix, by tumor cells.

What is osteosarcoma? 

100

Chondroblastoma is typically found in which area of the long bone?

What is the epiphysis of the long bone?

100

This classic periosteal reaction is associated with Ewing sarcoma.

What is onion-skinning?

200

Because they bounce high-frequency sound waves right back to the probe, structures like bone, gallstones, and fat show up on a sonogram (US) as this bright, white type of lesion.

What is hyperechoic?





200

Where do chondrosarcomas arise from?

What is chondrocytes (cartilage cells)?

200

This benign bone lesion is one of the most common tumors found in the calcaneus, particularly in younger patients.

What is a simple (unicameral) bone cyst?

200

This aggressive periosteal finding is classically associated with osteosarcoma.

What is a Codman triangle?

300

These two common types of benign tumors develop from cells associated with nerve sheaths.

What are schwannomas and neurofibromas?

300

This imaging study is commonly used to evaluate the lungs for metastatic disease in patients with sarcoma.

What is a chest CT scan?

300

These small bones of the fingers and toes are a common location for enchondromas.

What are the phalanges?

300

This matrix appearance should make you think fibrous dysplasia.

What is ground glass?

400

Describe Clark level 3. 

What is filling of the papillary dermis but NOT extending to reticular dermis?

400

This benign but locally aggressive bone tumor typically occurs in skeletally mature patients, after closure of the growth plates.

What is a giant cell tumor of bone?

400

A patient presents with ankle pain that worsens at night but is relieved by aspirin (ASA). This benign bone tumor can occur in the talus.

What is osteoid osteoma?

400

Pain in foot worse at night. Pain is relieved with ASA. What is your diagnosis? 

What is osteoid osteoma?

500

List the ABCDE criteria of malignant melanoma. 

What is asymmetry, border (irregular), color (variegated), diameter (> 6mm), and evolving over time?

500

This radiographic finding involves new bone formation along the outer surface of a bone in response to an underlying process.

What is a periosteal reaction?

500

This benign bone tumor most commonly develops near the metaphysis of long bones, particularly around the knee, and projects outward from the bone surface.

What is an osteochondroma?

500

This benign, blood-filled, expansile bone lesion can produce a “soap bubble” appearance on X-ray.

What is an aneurysmal bone cyst?