Bolus insulins
Basal insulins
A gut reaction
Release the insulin!
Miscellaneous
100
Medications with an amino acid structure identical to human insulin.
What are Humulin R and Novolin R
100
A medication that combines a bolus of Aspart with a basal of Degludec.
What is Ryzodeg?
100
This category of medications will increase the biological half-life of GLP-1 and GIP.
What are DPP-4 inhibitors?
100
The primary disease that GLP-1 receptor agonists, meglitinides and sulfonylureas are contraindicated for.
What is Type 1 Diabetes?
100
The mechanism of action for Canagliflozin (Invokana) and Dagapliflozin (Farxiga).
What is blocking SGLT2-dependent glucose reabsorption in kidneys?
200
The route of administration for Afrezza, and its time to peak absorption
Inhalation and 12-15 minutes
200
The generic name for Levemir.
What is Detemir?
200
Two medications that inhibit alpha-glucosidase
What are Acarbose (Precose) and Miglitol (Glyset)?
200
The category of drugs including Exenatide (Byetta), Exenatide ER (Bydureon) and Liraglutide (Victoza).
What are GLP-1 receptor agonists?
200
Two thiazolidinediones and their cellular target.
What are Pioglitazone (Actos), Rosiglitazone (Avandia) and PPAR-gamma?
300
This chemical modification extends the duration of regular insulin, and these are two examples.
What is NPH modification, and Humulin N and Novolin N.
300
The generic name for Lantus and Basaglar.
What is Glargine?
300
This drug mimics a hormone that is co-secreted with insulin from pancreatic beta cells. Functions include decreasing glucagon and gastric emptying while promoting satiety.
What is Pramlintide (Symlin)?
300
The drug category including Natglinide (Starlix) and Repaglinide (Prandin).
What are meglitinides.
300
A multifunctional drug that decreases hepatic glucose production and intestinal glucose absorption while improving insulin sensitivity.
What is Glucophage (Metphormin)?
400
This is the duration of regular insulin.
What is 6-8 hours?
400
The duration of action for Tresiba (Degludec)
What is 42 hours?
400
A bile acid sequestrant that blocks intestinal carbohydrate absorption.
What is Colesevelem (Welchol)?
400
Two drug categories that function by stimulating potassium channels on beta cells, leading to calcium-dependent insulin release.
What are sulfonylureas and meglitinides?
400
The medication most likely to be used in combination with other medications.
What is metphormin?
500
Insulin medications with amino acid substitutions that most likely reduce hexamer formation, leading to faster absorption than regular insulin.
What are Aspart (Novolog), Glulisine (Apidra) and Lispro (Humalog)?
500
Two properties of basal insulins that increase their duration of action.
What are precipitation/aggregation at the injection site and serum albumin-binding?
500
The names of all four DPP-4 inhibitors
What are Alogliptin (Nesina), Linagliptin (Tradjenta), Saxagliptin (Onglyza) and Sitagliptin (Januvia)?
500
Name two sulfonylureas.
What are Chlorpropamide (Diabinese), Tolazamide (Tolinase), Tolbutamide (Orinase), Glyburide (Diabeta, Glynase), Glipizide (Glucotrol) and Glimepiride (Amaryl)?
500
The cellular target for Bromocriptine (Cycloset).
What are dopamine receptors?