Ulcers and infection
Herpetic ulcers
Coxsakie and erythema multiform
Recurrent ulcers
Direct questions (all or nothing)
100

This is an irregular ulcer with indurated base and undermined edge and the dorsum of the tongue is the most common site 

Tuberculosis ulcer

100

What disease is usually present in children? *herpetic diseases only

ACUTE HERPETIC GINGIVOSTOMATITIS (AHGS)

100

What type of virus is coxsackie?

RNA virus

100

What is the most common reccurent ulcer?

Recurrent Aphthous Ulcer

100

Enumerate the lesions that heal with scar formation

Heal with scar formation:

• Herpes zoster

• Mucous Membrane Pemphigoid

• Major Recurrent Aphthous Ulcers

200

Which stage of syphillis can be treated with penicillin?

Chancre (primary stage)

200

Which lymph nodes does ACUTE HERPETIC GINGIVOSTOMATITIS affect? (Lymphadenopathy of the....) 

submandibular and upper deep cervical lymph nodes

200

Treatment of any disease caused by coxsackie?

No treatment is required

Topical anesthesia and mouth wash are used in severe cases

200

What are the etiological factors for RAU?

Hereditary, immunologic, hematologic, trauma, psychologic stress, anxiety, allergy to foods and hormonal disturbances.

200
Give two lesions that have indurated base other than SCC

• Chancre

• Major recurrent aphthous ulcer

• Long standing traumatic ulcer

• Tuberculosis

300

What is the primary site of inoculation and the primary site of infection of syphillitic chancre?

  • site of inoculation: genitalia
  • site of infection: vermillion border of the lips or the tongue
300
The phenomena of "rabit's kidney" can be seen in...?

Isolation of HSV in tissue culture of ACUTE HERPETIC GINGIVOSTOMATITIS (AHGS)

300

What is the chief complaint of someone with macules, papules and vesicles on skin of hands and feet and infection with coxsackie virus?

Sore mouth and refusal to eat

300

What is the etiology of the recurrent form of herpes labialis and how can we differenciate it from primary form?

 reactivation of the Latent virus

+

High antibody titer

NO systemic Prodromal features

300

There are 5 diseases that come with eye involvement. List them.

Associated with eye lesions:

• EM

• Herpes zoster

• MMP

• Behcet’s syndrome

• Reiter’s syndrome

400

Describe the expected clinical picture of tertiary syphillis. 

affects the hard palate causing Gumma which destroys the palatal bone, resulting in palatal perforation and/or the tongue resulting in single, deep ulcer with u-punched out margins 

400

What are the manifestations of herpes zoster virus when it affects the Mandibular division?

unilateral lesions in buccal mucosa, Tongue, Vestibule of the lower jaw, Skin lesions extending from the chin to the vertex.

400

Which types of erythema multiform are accompanied with systemic manifestations as fever and malaise?

Stevens Johnson syndrome, and toxic epidermal necrolysis (TEN)

400

Which disease caused the highest incidence in Asia and the Mediterranean of blindness in young men?

Behcet’s syndrome

400

Describe the depth of ulcers that come with chemotherapy and their characteristic smell

Deep with a foul smell.

500

What are the clinical features of viral infections?

Prodrome

Vesicle formation. 

Ulcers: small, shallow, rounded and surrounded by erythema (red halo).

Pain 

Increased salivation.

Self-limiting disease, heal with or without scar formation without treatment.

500

What is the clinical picture of RECURRENT INTRAORAL HERPES?

Vesicles on the keratinized mucosa (tongue, hard palate and gingiva) that may occur in clusters.

Vesicles rupture forming multiple (dozens) ulcers which are pin-head size and surrounded by erythema. Ulcers tend to coalesce forming larger ulcers which appear irregular, superficial, surrounded by erythema and extremely painful.

Ulcers heal without scar formation in 7 – 14 days. 

500

EM must be differentiated from AHGS since steroids used in the treatment of EM are contraindicated in AHGS. How can we differentiate them?

AHGS ulcers are small, shallow, round and affect both keratinized and non-keratinized oral mucosa and generalized gingival involvement is characteristic.

EM ulcers are large, irregular, deeper, and often bleed and ulcers may occur anywhere on the oral mucosa mainly the lips (bloody crusted lips) and the gingival involvement is rare.

500

Disease characterized by arthritis, urethritis, conjunctivitis together with oral aphthous like ulcers

Reiter’s syndrome

500

Which ulcer is characterized by these properties:

Shallow with bleeding.

Deep

Not surrounded by a red halo

has peripheral extension


Pemphigus vulgaris