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Anemias
Scenarios
100
What are two unique qualities of RBCs
1. High-Surface to volume ratio 2. Reversible Deformity
100
A patient is having RLQ pain, which is an indicator for appendicitis. What lab test might you order?
White blood cell differential, Size and complexity.
100
What would be the condition if I had a shift to the left, or bands of neutrophils?
Neutrophilia
100
Someone has petechiae, pancytopenia and just finished a round of chemotherapy what anemia is present?
Aplastic
100
Julie an avid runner, was feeling a little down and fatigued. After about 2 weeks she went to her doctor who ordered a complete workup. Her workup returned and it is noted that her RBC, Platelet, Macrocytes, Neutrophils, Eosinophils, Basophils are lower when compared to normal values, her genetic test indicated that their was a translocation of the chromosomes 9 and 22. What Does she have
CML
200
What are the three main types of cells in this unit?
RBC, WBC, platelet
200
Which of the following is not assessed in bone marrow biopsies, Anemia, Lymphoma, Leukemia, Platelet disorder, Immunoglobin Disorder.
Lymphoma
200
Which cancer affects children more than adults
ALL
200
I have an infant who had a complete workup and it was detected that the patient had autoantibodies against gastric parietal cells. What anemia might be present?
Pernicious
200
John a guitarist for a tribute band to ACDC and who has had a previous treatment of infectious mononucleosis, has been having perfuse night sweats. He went to his doctor who performed a test to check his lymph nodes for the prescience of cancer. Why did the doctor do this, and what involvement will he see.
EBV is correlated with Hodgkin's lymphoma and localized.
300
Rank the Leukocytes from greatest concentration to least
Neutrophils, Lymphocytes, Monocytes/macrophage, eosinophils, basophil
300
What do Bence Jones proteins indicate?
Multiple Myeloma
300
What condition would I have if Reed Sternberg cells were present?
Hodgkin's lymphoma
300
A patient's lab just came back and the following is noted" Fe concentration in blood is normal, and a decreased heme". You then look at their MRI and the radiologists put a note in saying evidence of hepatosplenomegaly What anemia is present?
Sideroblastic
300
A patient is rushed into the ER and is immediately ordered a blood panel analysis, and through the power of medicine it comes back within 10 seconds. it is noted that the patient's FDP levels are elevated, and is having widespread ischemia. What is present.
DIC
400
List the pathway of coagulation
prothrombin to thrombin to fibrinogen to fibrin
400
Which of the RBC laboratory values does not pertain to hemoglobin?
MCV
400
If I have a sickle cell and I become hypoxic, or deoxygenated what might happen?
Vasoocclusive crisis
400
Which of the following does not belong with this group? Vitamin B12, Folic Acid, Iron.
Iron- this is a microcytic while the others are macrocytic anemias.
400
A 50 year old European man comes into the hospital to review his most recent lab tests. The doctor tells him that the test indicate he has a hypersensitive bone marrow, that is rare that he has this condition. What condition does he have?
PCV
500
Name all the nutrients in anemia and what they do, and what anemia they correlate with. Hint there are 3
B12- DNA synthesis-macrocytic Folic Acid- DNA,RNA synthesis-macrocytic Iron- Hgb synthesis- microcytic hypochromic
500
If someone has EBV what would you expect to find on their monospot test?
Heterophilic antibodies
500
If I have a defect in the Beta chain what is going to happen to my alpha chain in thalassemia?
It will increase
500
Name a distinguishing quality of all the following anemias, microcytic, macrocytic, normocytic.
Micro- Metals, Macro-Vitamins, Normo- Stimulus, secondary to.
500
Someone is rushed into the ER after just being bitten by a snake. What is the big deal with this, and explain why?
Snake venom will activate Factor X, or the common pathway. This will cause hypercoagulability and the patient might develop a thrombus, or embolus.