Cholesterol
PCR
Familial
Hypercholesterolemia
Vocabulary
Double Jeopardy
100
What is cholesterol
What is a fatty steroid that serves many uses in the body
100
What does PCR stand for
What is Polymerase Chain Reaction
100
What is Familial Hypercholesterolemia
What is a inherited disease that has high LDL levels and can cause early cardiovascular disease
100
Three fatty acids linked to one glycerol molecule.
What is a trigyleride
100
These are the molecules also monitored with LDL and HDL levels
What are triglycerides
200
What does LDL stand for
What is low density lipoprotein
200
What is a restriction enzyme
What is a catalyst that cuts DNA at a specific region
200
Name two complications of FH
What is heart attack, stroke, heart disease
200
What is a polysaccharide obtained from seaweed that is used as the supporting medium in gel electrophoresis
What is agarose
200
What is gel electrophoresis
What is a method to separate and analyze DNA by the size of the fragments and their charge
300
What does HDL stand for?
What is high density lipoprotein
300
Besides DNA, what are the three components necessary for PCR?
Primers, DNA polymerase, and nucleotides
300
If a man ,that does not have FH, marries a woman heterozygous FH, what are the chances that their children will be afflicted with the disease
What is 50% . Familial Hypercholesterolemia is an autosomal dominant mutation
300
Alternative versions of a gene that produce distinguishable phenotypic effects.
What is allele
300
What is a lipoprotein
What is a group of soluble proteins that combine with and transport fat or other lipids in the blood plasma.
400
Name at least two functions of cholesterol
What is repairing cell membranes,hormone synthesis,manufacturing of Vitamin D,bile production,antioxidants,etc.
400
An enzyme that acts as a glue that sticks DNA back together
What is ligase
400
How does FH cause heart disease
What is FH can cause to high levels of LDL "bad cholesterol" because the body is unable to get rid of it and that can contribute to plaque build up in the arteries
400
The movement of suspended particles through a fluid or gel under the action of an electromotive force applied to electrodes in contact with the suspension.
What is electrophoresis
400
Cholesterol is produced in the __________
What is the liver
500
What is the difference between saturated fats and unsaturated fats
What is saturated fats have lots of hydrogen atoms and do not contain double bonds between carbon atoms. They are not heart healthy, since the raise the LDL levels. While unsaturated fats have double bonds between the carbon atoms and are consider good, since they raise HDL levels.
500
Name three uses of PCR
What is paternity testing,genetic fingerprinting, DNA cloning,analysis of genes,disgnosis of diseases,etc.
500
What chromosome is FH located on
What is chromosome 19
500
A long carbon chain with the end carbon double bonded to oxygen and to a hydroxyl (OH) to form a carboxylic acid. Fatty acids vary in length and in the number and location of double bonds; three fatty acids linked to a glycerol molecule form fat.
What is a fatty acid
500
What does RFLP stand for
What is Restriction Fragment Length Polymorphism