Metabolism/Bacterial Control
The part of the enzyme where the substrate binds.
What is the ACTIVE SITE?
The enzyme that synthesizes DNA.
What is DNA Polymerase.
Iodine, fluorine, and chlorine are examples.
What are halogens?
Penicillin acts by inhibiting the building of this bacterial cell structure.
What is the cell wall?
Out of these three administration methods (oral, intramuscular, and intravenous), this method gets the drug into the bloodstream the most quickly.
What is intravenous?
Binds the active site of RNA Polymerase.
What is RNA?
The process where bacteria, such as E. coli, can be infected by a virus.
What is TRANSDUCTION.
A physical or chemical method that destroys vegetative pathogens but NOT endospores.
What is Disinfection?
The inhibition of protein synthesis acts on these organelles.
What are ribosomes?
One way that bacteria become antibiotic resistant.
What is through mutations, drug inactivation, efflux pumps, blocking drug entry, or using different metabolic pathway?
How enzymes work.
What is by lowering the Activation Energy?
Term that describes bacterial genes that are organized close together in a chromosome and that are transcribed at the same time.
What is an OPERON?
Systemic inflammation caused by an infection that leads to organ failure, shock and death.
What is SEPSIS.
Using an antibiotic after surgery to prevent an infection
What is Prophylaxis?
Type of antibiotics, such as Penicillin, that block peptidoglycan synthesis.
What are the Beta-lactams?
Exposing bacteria to UV light can cause these to form in the bacterial DNA.
What are Thymine dimers?
Enzyme that joins the Okazaki fragments during Replication.
What is Ligase?
The gas commonly used to sterilize plastic materials such as catheters.
What is Ethylene Oxide?
Amphotericin B disrupts the cytoplasmic membrane by forming holes in these types of microorganisms.
What are FUNGI?
Bacterial pathogens can become resistant to antibiotics via the acquisition of these:
What are plasmids?
Secreted enzymes or toxins that make bacteria more pathogenic. [General term or specific enzyme]
What are virulence factors?
Examples Collagenase, Streptokinase, botulinum, tetanus
DNA is tightly coiled around these proteins.
What are histones?
Common degerming agent used to scrub skin before surgery.
What is Chlorhexidine.
An antibiotic that blocks the synthesis of folic acid in the bacterial cell is this type.
What is a compound that affects metabolism or metabolic pathway?
Miconazole is an antimicrobial that works by blocking the synthesis of this cellular component.
What is fungal Ergosterol?