What is alopecia?
Hair loss
What is the shrinkage of tissues or organs after irradiation?
Atorphy
At which stage of ARS does the patient feel a sense of well-being?
Latent stage
What stage of cell division do we use for mapping chromosomes?
Metaphase
Who are somatic effects referring to?
The irradiated person
Which system would show a decrease in the number of lymphocytes?
HE syndrome
What is a threshold in a deterministic effect?
determined or known dose to cause an effect
In the HE system, which cell is the most radiosensitive?
Lymphocytes
What is the correct term for the mapping of chromosomes?
Karyotype
In diagnostic x-ray, what is the only procedure or type of equipment that would cause a deterministic effect?
High Level Control Fluoro
Which effects appear early and are directly proportional to dose?
Deterministic
What is an example of a deterministic effect?
- Erythema
- Epilation
- Desquamation
- Radiodermitis
- ARS
Name a symptom of GI syndrome:
Emaciation
Loss of appetite
Lethargy
Fatigue
Fever
What would be a symptom of CSV syndrome?
Confusion
Coma
Disorentation
Loss of consciousness
Fluid buildup around the brain
Loss of vision
What would be a symptom of HE syndrome?
Decrease # of blood cells, platelets, lymphocytes, leukocytes
Hemorrhage
Low O2 levels
Which ARS syndrome requires the largest dose in order to show effects?
What is that dose?
Cerebrovascular (CSV)
50Gy
What are the 4 major stages that ARS presents in?
- Prodromal
- Latent
- Manifest Illness
- Recovery/ Death
What is a collection of symptoms from a high WB dose of radiation delivered all at once?
Acute Radiation Syndrome
The ovarian system multiplies to millions of egg cells during which stage of development?
Fetal Stage
What are the 3 broad symptoms of ARS or radiation sickness?
- loss of appetite
- diarrhea
- nausea
What is the threshold dose for desquamation?
What about for erythema?
15 Gy
2 Gy
Survival time for each sub-syndrome of ARS:
HE
GI
CSV
6-8 weeks
3-10 days
hours to 3 days
(know doses as well!)
What is the cause of death for:
HE
GI
CSV
Bone marrow failure
Intestinal crypt cell destruction (epithelial lining)
Destruction to the cardiovascular & CNS systems (fluid buildup)
When is a sperm cell the most radiosensitive? What stage of its life?
Spermatogonia
Threshold dose for temporary epilation:
3 Gy