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Therapeutic Drug Monitoring
Toxicology
Vitamins
Tumor Markers
Miscellaneous
100
1- Selectively as to site of action 2- Reversibility in its action 3- production of therapeutic effect
What makes a chemical a drug?
100
The study of poisonous substances?
What is Toxicology
100
Water soluble Referred to as Pyridoxine
What is Vitamin B6
100
A substance synthesized by the tumor or by the host in response to a tumor that can be used to detect the presence of the tumor.
What is a Tumor Marker?
100
The amount excreted depends on the amount taken in/present
What is first order kinetics?
200
When are steady state drug levels achieved?
What is after 5-7 half lives?
200
1 - Gasses 2- Volatiles 3- Corrosives 4- Metals 5- Nonmetals 6- Non volatile organics
What are the 6 classes of poisons?
200
Deficiency/inbalance of one or more vital nutrients (proteins, vitamins, and minerals)
What is Malnutrition
200
What causes changes in gene expression?
What is a normal cell that is transformed into a tumor cell?
200
COCAINE (drugs of abuse)
What is a nonvolatile inorganic poison used for recreation/suicide?
300
The Liver
What is the major site of drug biotransformation?
300
Thin-layer Chromatography
What is the test that is used for mass screenings?
300
Fat soluble Found in green leafy vegetables, liver, cheese, butter, and eggs Promotes blood clotting
What is Vitamin K?
300
1. Screening for disease in asymptomatic population 2. Diagnosis of disease 3. Aid in clinical staging 4. Measurement of tumor burden 5. Therapeutic monitoring and selection. 6. Detection of relapse. 7. Prognostic indicator
What is Clinical applications of tumor markers?
300
Abundant and Trace
What are two groups that minerals are decided into?
400
Used to treat manic depressive illness. Absorption complete and rapid.
What is Lithium
400
Spot Tests
What are the easiest and least complex toxicology tests?
400
Enhance the activity of selected enzymes by serving as precursors/components of co-enzymes or prosthetic groups.
What is members of the vitamin B complex?
400
What remains confined to its primary site during the life span of the organism?
What is a benign neoplasm?
500
Used for treatment of infections with Gram Negative Bacteria
What are Aminoglycosides?
500
Most common screening method for drugs of abuse
What are Immunoassays?
500
Subjective approach and subjective assessment
What are the two approaches to nutritional assessment and monitoring?
500
Oncogenes and anti-oncogenes
What are the two types of genetic tumor markers?
500
Staging system that uses subscripts to describe presence, size and degree of invasiveness of primary tumor, regional lymph-nodes, and distant metastases
What is the TNM System?