Autoimmune condition in which most patients have positive anti–cyclic citrullinated peptide antibodies
Rheumatoid arthritis
Victorian-era toy creating sound akin to pulses felt in aortic regurgitation
Water hammer
Diagnosis with low TSH but normal T4 and T3 levels
Subclinical hyperthyroidism
Bacteria, eradication of which is key to the treatment of MALT lymphoma
Helicobacter pylori (accept H. pylori)
Blood pressure medication that lowers uric acid
Losartan
HLA subtype positive in 92% of White persons with axial spondyloarthritis
HLA-B27 (accept B27)
Creator of the smallpox vaccine
Edward Jenner (accept Jenner)
Thionamide medication to treat hyperthyroidism in pregnancy
Propylthiouracil (accept PTU)
Most common infectious cause of type II mixed cryoglobulinemia
Hepatitis C
More potent opioid that results from hepatic cytochrome P450 2D6 conversion of hydrocodone
Hydromorphone
Condition characterized by objective keratoconjunctivitis sicca and xerostomia with autoantibodies
Sjögren syndrome
Nursing namesake for the palpable umbilical nodule indicative of metastatic cancer
Sister Mary Joseph (accept Julia Dempsey or Dempsey)
Monoclonal antibody that inhibits osteoclast activation
Denosumab
Organ serving as a reservoir for chronic Salmonella typhi infection
Gallbladder
Target of monoclonal antibody treatment for migraine prophylaxis
Calcitonin gene-related peptide (accept CGRP)
Disease associated with the pictured findings and muscle weakness
Dermatomyositis
Class of oncologic medication whose discovery earned Professor James Allison the Nobel Prize in Physiology or Medicine in 2018
Immune checkpoint inhibitors
Eponymous decrease in thyroid hormone production due to an exogenous iodine load
The Wolff-Chaikoff effect
Pharmacologic prophylaxis for encephalopathy for those at risk after hepatic shunt placement
Rifaximin
Antiarrhythmic medication associated with drug-induced lupus and antihistone antibodies
Procainamide
Antibodies against this nuclear enzyme put scleroderma patients at highest risk of cancer within 3 years of disease onset
RNA pol III (RNA polymerase III)
1990 Nobel laureate who performed the first human kidney transplantation in the U.S.
Joseph Edward Murray (accept Joseph Murray or Murray)
Required cancer screening in individuals with growth hormone excess
Colonoscopy (accept colon cancer screening)
Eponymous triad of hemolytic anemia, jaundice, and hypertriglyceridemia with heavy alcohol use
Zieve syndrome
High-intensity statin metabolized by CYP2C9 system
Rosuvastatin