Viral Atherogenesis
Let's Get High
Effuse My Heart
Hemodynamize
Fire Around
100

Global population-attributable fraction of CVD due to HIV is approximately this percentage

1%

100

One of the most common EKG associations in patients with a history of marijuana use

Atrial fibrillation (Studies have found temporal relation to marijuana and afib in up to 26% of cases. VT and SCD have been attributed in case reports)

100

In the developing world, this infection remains a major cause of pericardial effusion.

tuberculosis

100
Absent Y descent is seen in this pericardial condition

Tamponade

100

4 criteria of acute pericarditis

Chest pain, pericardial friction rub, ECG changes, effusion (>=2/4 diagnostic)

200

The protease inhibitors indinavir and lopinavir/ritonavir are linked to this metabolic disorder.

Diabetes (insulin resistance)? CD4 count

200

Prolonged QT interval increasing the risk of torsades, VT, and SCD is associated with this drug of abuse

Opiates (Especially methadone, increase this risk. Morphine and buprenorphone are lower risk compared to others)

200

In tamponade, the equalization of left and right atrial and ventricular diastolic pressures with pericardial pressure typically occurs in this pressure range

20–25 mmHg

200

Definition of pulsus paradoxus - the pathology it's commonly seen

Abnormally large drop in systolic blood pressure (more than 10 mmHg) during inspiration 

200

High risk/major poor prognostic signs of acute pericarditis (give 3)

Fever >38 C, Subacute onset, Large pericardial effusion, Cardiac tamponade, Lack of response to ASA or NSAIDs within a week

Minor - myopericarditis, immunosuppression, trauma, oral anticoagulant therapy

300

This type of plaque is three times more likely to be found in patients with HIV

NONcalcified plaques

300

A drug of abuse which has been most associated with coronary dissection, pulmonary hypertension, heart failure, and ischemic cardiomyopathy via increased cardiomyocyte induction of apoptosis

Methamphetamine

300

The first Korotkoff sound is auscultated during which breathing cycle in tamponade

Expiration

300

Deep Y descent seen, no normalization seen after effusion drainage

Effusive-constrictive pericarditis

300

1st line therapy of acute pericarditis (with standard doses)

NSAIDs 

1. ASA 750-1000 mg Q8h x 1-2 weeks - taper

2. Ibuprofen 600-800 mg Q8h x 1-2 weeks - taper

+ colchicine 0.6 mg BID (if >70 kg) x 3 months - then reconsider

400

This screening method for cardiovascular disease is an independent predictor of mortality in patients with HIV

Carotid intima-media thickness

400

This condition is seen in young males within days to weeks of using E cigarettes presenting with dyspnea, chest pain, fatigue, cough, fever, gastrointestinal symptoms and ground-glass opacities on chest x-ray.

E-cigarette or vaping product use associated lung injury (EVALI)

400

Both tamponade and constriction show equalization of left and right filling pressures, but this jugular venous sign is typically absent in tamponade and present in constriction

Kussmaul’s sign

400

Finding

Intrathoracic-intracardiac dissociation (Inspiration reduced left sided filling gradient compared with the increased gradient with expiration as the fall intrathoracic pressure is transmitted to the pulmonary veins but poorly to the LV)

400

Four stages of ECG changes in acute pericarditis

1. PR depression and/or diffuse ST segment elevation

2. Normalization of ST segment

3. T wave inversion with or without ST segment depression

4. Normalization

500

Coinfection with this virus is associated with coronary artery calcification and carotid intima-media thickening in patients with HIV

CMV

500

Energy drinks have been implicated as culprits behind MI via this mechanism

Platelet aggregation and arachidonic acid activation (accept any one)

500

On echocardiography, these two chamber collapses appear early in tamponade—name each chamber and the timing within the cardiac cycle

Early diastolic RV collapse and late diastolic (early systolic) RA collapse

500

Finding

Enhanced ventricular interdependence

500

An IL-1a and IL1-b cytokine trap, recently shown to be beneficial in recurrent pericarditis

Rilonacept