Play song
Nancy Ajram
angioedema
ACEi
Start 25mg daily
Target dose: 50mg daily
Eplerenone (Inspra)
Block activation of RAAS, resulting in vasodilation and improved EF
ACEI/ARB
concomitant use with an ACEi
ARB
Starting dose 12.5-25mg/day
Target dose 200mg daily
Metoprolol succinate (Toprol XL)
Inhibition of neprilysin increases levels of natriuretic peptides and bradykinin, counteracting neurohormonal overactivation that contributes to vasoconstriction and Na retention
ARNI
Do not initiate treatment in heart failure pts with K > 5mEq/L; SCr> 2.) mg/dL (females) or SCR >2.5mg/dL (males)
Aldosterone antagonist
Start 25-50 mg QD
Target dose: 50-150 daily
Losartan (cozaar)
competitively blocks beta1-receptors
Beta Blocker
ventricular fib
Digoxin
Start 2.5-5mg daily
Target dose: 20-40 mg daily
Lisinopril (Prinivil)
Competes with aldosterone for receptor sites in the distal renal tubules, increasing sodium chloride and water excretion while conserving potassium and hydrogen ions
Aldosterone antagonists
BP <90/50mmHg; HR <60 BPM prior to treatment
Ivabradine
Oral: 20-40mg QD or BID
max single dose 160-200mg
Furosemide (Lasix)